Results 81 to 90 of about 3,370,652 (304)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Reliable identification of the auditory thalamus using multi-modal structural analyses. [PDF]

, 2006
The medial geniculate body (MGB) of the thalamus is a key component of the auditory system. It is involved in relaying and transforming auditory information to the cortex and in top-down modulation of processing in the midbrain, brainstem, and ear ...
Johansen-Berg, Heidi, Hall, D A, Nunes, R. G., Johansen-Berg, H, Devlin, JT, Clare, S., Behrens, T. E. J., Matthews, P. M., Nunes, RG, Johansen-Berg, H., Sillery, E L, Devlin, J. T., Moore, DR, Hobden, P., Matthews, PM, Behrens, TEJ, Clare, S, Matthews, P M, Hobden, P, Moore, D R, Nunes, R G, Hall, DA, Hall, D. A.; id_orcid, Devlin, J T, Sillery, E. L., Sillery, EL, Behrens, Timothy, Behrens, TE, Behrens, T E J, Moore, D. R.   +29 more
core   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han, Jiachun Pan, Yuehui Hong, Xiaoyuan Fan, Ming Yao, Lixin Zhou, Yicheng Zhu, Feng Feng, Jun Ni   +8 more
wiley   +1 more source

Defining Meyer's loop-temporal lobe resections, visual field deficits and diffusion tensor tractography [PDF]

, 2009
Anterior temporal lobe resection is often complicated by superior quadrantic visual field deficits (VFDs). In some cases this can be severe enough to prohibit driving, even if a patient is free of seizures.
M Yogarajah (16050209), J S Duncan (16050227), McEvoy, A.W., M J Koepp (13602235), Focke, N.K., Koepp, M. J., Duncan, John S., M R Symms (16042382), Koepp, Matthias J., Duncan, J.S., Symms, M.R., Alexander, D. C., Parker, G. J M, Acheson, J., Bonelli, S., A W McEvoy (16050224), S Bonelli (16050215), G J M Parker (16050218), Mara Cercignani (4463104), Alexander, Daniel C., Alexander, D.C., Koepp, M.J., McEvoy, A. W., Parker, G.J.M., J Acheson (10343627), Yogarajah, Mahinda, Symms, Mark R., Bonelli, Silvia B., Cercignani, M., D C Alexander (16050221), Yogarajah, M., Focke, N. K., Symms, M. R., Focke, Niels K., Duncan, J. S., N K Focke (16050212), Parker, G. J. M.   +36 more
core   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Role of diffusion-weighted MR imaging in discrimination between the intracranial cystic masses

The Egyptian Journal of Radiology and Nuclear Medicine, 2014
Objective: Discriminating pyogenic brain abscesses from cystic or necrotic tumors is sometimes difficult with CT or conventional MR imaging. Diffusion MR imaging is a valuable diagnostic test in cases of intracranial cystic masses. Methods: This work was
Ahmed Farid Yousef, Amany Elkharbotly, Magdy Settin, Yasser Mousa   +3 more
doaj   +1 more source

The use of conventional and advanced magnetic resonance techniques in the assessment of primary brain tumours [PDF]

, 2008
The aim of the work described in this thesis was to investigate the value of conventional, perfusion- and diffusion-weighted magnetic resonance imaging (MRI) in patients with histology-proven low-grade gliomas (LGG), and the potential role of these ...
Caseiras, G.D.B.
core  

Fusion of Diffusion-Weighted Magnetic Resonance Imaging and High-Resolution Computed Tomography Scan As a Preoperative Tool for Classification of Middle Ear Cholesteatoma

, 2022
BACKGROUND: The role of imaging in cholesteatoma continues to evolve with excellent bony details provided by high-resolution computed tomography and high soft tissue identification for cholesteatoma by diffusion-weighted magnetic resonance imaging.
Ahmed Galal, Mohamed Eid, Galal, Ahmed, Mohamed Badr-El-Dine, Eid, Mohamed, Omran, Ahmed, Badr-El-Dine, Mohamed, Mohamed ElNaggar, Ahmed Omran, ElNaggar, Mohamed   +9 more
core   +1 more source

Added Prognostic Value of EEG Reactivity in Comatose Patients Following Cardiac Arrest

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To evaluate the added prognostic value of EEG reactivity for favorable outcome compared with background analysis during and after targeted temperature management (TTM). Methods Prospective observational cohort study of comatose post–cardiac arrest patients admitted to a single academic center between 2017 and 2022, all undergoing ...
Sarah Caroyer, Marie Obrecht, Charlotte de Maeseneire, Charlotte Damien, Chantal Depondt, Lorenzo Ferlini, Estelle Rikir, Filippo Annoni, Fabio Silvio Taccone, Nicolas Mavroudakis, Benjamin Legros, Nicolas Gaspard   +11 more
wiley   +1 more source

Diffusion weighted imaging: Technique and applications

World Journal of Radiology, 2016
Diffusion weighted imaging (DWI) is a method of signal contrast generation based on the differences in Brownian motion. DWI is a method to evaluate the molecular function and micro-architecture of the human body. DWI signal contrast can be quantified by apparent diffusion coefficient maps and it acts as a tool for treatment response evaluation and ...
Baliyan, Vinit, Das, Chandan J, Sharma, Raju, Gupta, Arun Kumar   +3 more
openaire   +2 more sources