Results 91 to 100 of about 184,272 (299)

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Delta-radiomics features of ADC maps as early predictors of treatment response in lung cancer

Insights into Imaging
Objective Investigate the feasibility of detecting early treatment-induced tumor tissue changes in patients with advanced lung adenocarcinoma using diffusion-weighted MRI-derived radiomics features.
Christian M. Heidt, Jonas R. Bohn, Róbert Stollmayer, Oyunbileg von Stackelberg, Stephan Rheinheimer, Farastuk Bozorgmehr, Karsten Senghas, Kai Schlamp, Oliver Weinheimer, Frederik L. Giesel, Hans-Ulrich Kauczor, Claus Peter Heußel, Gudula Heußel   +12 more
doaj   +1 more source

Diffusion-weighted MRI in assessment of renal dysfunction

Indian Journal of Radiology and Imaging, 2012
Background: Diffusion-weighted magnetic resonance imaging (DW-MRI) in renal diseases is an evolving field and its potential is yet to be fully realized.
Ankur Goyal, Raju Sharma, Ashu Bhalla, Shivanand Gamanagatti, Amlesh Seth   +4 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Comparing T2 weighted images/diffusion weighted imaging and T2 weighted images/dynamic contrast enhanced MRI for endometrial carcinoma myometrial invasion

The Egyptian Journal of Radiology and Nuclear Medicine, 2017
Objectives: To evaluate accuracy of combined T2 and diffusion weighted images (DWI) in comparison to combined T2WI and dynamic contrast enhanced-magnetic resonance imaging (DCE-MRI) for assessment of the depth of myometrial invasion.
Mohamed Aboul-Fotouh Mourad, Elsayed M. Mousa   +1 more
doaj   +1 more source

Deep Learning How to Fit an Intravoxel Incoherent Motion Model to Diffusion-Weighted MRI

, 2019
Purpose: This prospective clinical study assesses the feasibility of training a deep neural network (DNN) for intravoxel incoherent motion (IVIM) model fitting to diffusion-weighted magnetic resonance imaging (DW-MRI) data and evaluates its performance ...
Barbieri, Sebastiano, Gurney-Champion, Oliver J., Klaassen, Remy, Thoeny, Harriet C.   +3 more
core   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Diffusion-Weighted Magnetic Resonance Imaging Value in the Detection and Differentiation of Bone Tumors and Tumor-Like Lesions

Erciyes Medical Journal, 2019
Objective: The aim of this study was to evaluate the ability of diffusion-weighted magnetic resonance imaging (MRI) and its corresponding apparent diffusion coefficient (ADC) values in the detection, characterization, and discrimination between different
Mostafa Emara, Ayman Nada, Maged Hawana, Mohamed Elazab, Ahmed Mohamed Shokry   +4 more
doaj   +1 more source

Analysis Of Fractional Anisotropy (Fa) Values And Apparent Diffusion Coefficient (Adc) Values In Ischemic Stroke Diseases Of Mri Ge 3 Tesla [PDF]

, 2019
Background: Diffusion Weighted Imaging and Diffusion Tensor Imaging is an advanced technique in MRI that shows the diffusion in brain of ischemic stroke disease.
Latifah, R. (Risalatul), Muhaimin, M. (Muhaimin), Mustofa, A. (Ali), Sensusiati, A. D. (Anggraini), Utomo, S. A. (Sri)   +4 more
core