Results 61 to 70 of about 977,209 (268)

Minería y vulnerabilidad de los territorios rurales en los Andes ecuatorianos: evidencias desde la provincia del Azuay

Cuadernos de Geografía: Revista Colombiana de Geografía, 2018
En los Andes ecuatorianos, la agricultura familiar se encuentra desde hace varias décadas en una situación de gran vulnerabilidad. A pesar de la reciente renovación del discurso político en Ecuador y del advenimiento de la era del “Buen Vivir”, el auge ...
Julio A. Alvarado Vélez, Nasser Rebaï
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Short communication: Bifidobacterium abundance in the faecal microbiota is strongly associated with milk traits in dairy cattle

Animal
The performance of dairy cows is influenced by the microbial communities hosted within their digestive tract. While the rumen microbiota has long been associated with host phenotypes, the impact of the faecal microbiota remains elusive. In this study, we
L. Brulin, S. Ducrocq, G. Even, M.P. Sanchez, S. Martel, S. Merlin, C. Audebert, P. Croiseau, J. Estellé   +8 more
doaj   +1 more source

A statistical approach to surface renewal: The virtual chamber concept

Agrosystems, Geosciences & Environment, 2021
In the stable conditions prevailing at night, concentrations of emitted gases (e.g., radon [Rn], carbon dioxide [CO2], methane [CH4], ammonia [NH3], and nitrous oxide [N2O]) build up at the surface, with intermittent interruptions due to the passage of ...
Bruce B. Hicks, Nebila Lichiheb, Deb. L. O'Dell, Joel N. Oetting, Neal S. Eash, Mark Heuer, LaToya Myles   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Sequence-based genome-wide association study reveals host genomic regions and candidate genes influencing the fecal microbiota of Holstein cows

Journal of Dairy Science
: In recent decades, the digestive tract microbiota of livestock has been extensively studied, revealing associations with host phenotypes, including production- and health-related traits.
L. Brulin, M.-P. Sanchez, Z. Cai, S. Ducrocq, G. Even, S. Martel, S. Merlin, C. Audebert, J. Estellé, G. Sahana, P. Croiseau   +10 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Lessons from analysing mortality from six major flood events in France(1930-2010)

E3S Web of Conferences, 2016
Evolution of flood mortality is complex as several opposite factors come into play. On one side, flood risk has been aggravated due to an increase of the number of inhabitants within the area at risk, and to an increasing of simple-storey houses without ...
Boudou Martin, Lang Michel, Vinet Freddy, Coeur Denis   +3 more
doaj   +1 more source

Permafrost nitrous oxide emissions observed on a landscape scale using the airborne eddy-covariance method [PDF]

Atmospheric Chemistry and Physics, 2019
The microbial by-product nitrous oxide (N2O), a potent greenhouse gas and ozone depleting substance, has conventionally been assumed to have minimal emissions in permafrost regions. This assumption has been questioned by recent in situ studies which have
J. Wilkerson, R. Dobosy, R. Dobosy, D. S. Sayres, C. Healy, E. Dumas, E. Dumas, B. Baker, J. G. Anderson, J. G. Anderson, J. G. Anderson   +10 more
doaj   +1 more source

Diffusion to Capture and the Concept of Diffusive Interactions [PDF]

, 2019
Diffusion to capture is an ubiquitous phenomenon in many fields in biology and physical chemistry, with implications as diverse as ligand-receptor binding on eukaryotic and bacterial cells, nutrient uptake by colonies of unicellular organisms and the functioning of complex core-shell nanoreactors. Whenever many boundaries compete for the same diffusing
Galanti, Marta, Fanelli, Duccio, Traytak, Sergey D., Piazza, Francesco   +3 more
openaire   +2 more sources