Results 81 to 90 of about 4,097,489 (343)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Lessons from analysing mortality from six major flood events in France(1930-2010)

E3S Web of Conferences, 2016
Evolution of flood mortality is complex as several opposite factors come into play. On one side, flood risk has been aggravated due to an increase of the number of inhabitants within the area at risk, and to an increasing of simple-storey houses without ...
Boudou Martin, Lang Michel, Vinet Freddy, Coeur Denis   +3 more
doaj   +1 more source

Permafrost nitrous oxide emissions observed on a landscape scale using the airborne eddy-covariance method [PDF]

Atmospheric Chemistry and Physics, 2019
The microbial by-product nitrous oxide (N2O), a potent greenhouse gas and ozone depleting substance, has conventionally been assumed to have minimal emissions in permafrost regions. This assumption has been questioned by recent in situ studies which have
J. Wilkerson, R. Dobosy, R. Dobosy, D. S. Sayres, C. Healy, E. Dumas, E. Dumas, B. Baker, J. G. Anderson, J. G. Anderson, J. G. Anderson   +10 more
doaj   +1 more source

Retarding Sub- and Accelerating Super-Diffusion Governed by Distributed Order Fractional Diffusion Equations

, 2002
We propose diffusion-like equations with time and space fractional derivatives of the distributed order for the kinetic description of anomalous diffusion and relaxation phenomena, whose diffusion exponent varies with time and which, correspondingly, can
A. Ayache, A. Compte, A. V. Chechkin, A. V. Chechkin, B. J. West, C. Fox, E. Barkai, E. Barkai, E. Lutz, E. W. Montroll, F. Igloi, F. Mainardi, F. Mainardi, G. Zumofen, I. M. Sokolov, I. M. Sokolov, J. Dräger, J. Klafter, J.-P. Bouchaud, K. Diethelm, M. Caputo, M. Caputo, R. Gorenflo, R. Hilfer, R. L. Bagley, R. L. Bagley, R. Metzler, R. Metzler, T. Prosen, Y. G. Sinai   +29 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Testing and development of transfer functions for weighing precipitation gauges in WMO-SPICE [PDF]

Hydrology and Earth System Sciences, 2018
Weighing precipitation gauges are used widely for the measurement of all forms of precipitation, and are typically more accurate than tipping-bucket precipitation gauges.
J. Kochendorfer, R. Nitu, R. Nitu, M. Wolff, E. Mekis, R. Rasmussen, B. Baker, M. E. Earle, A. Reverdin, K. Wong, C. D. Smith, D. Yang, Y.-A. Roulet, T. Meyers, S. Buisan, K. Isaksen, R. Brækkan, S. Landolt, A. Jachcik   +18 more
doaj   +1 more source

Gravitation as a Quantum Diffusion

, 2003
Inhomogeneous Nelson's diffusion in flat spacetime with a tensor of diffusion can be described as a homogeneous one in a Riemannian manifold with this tensor of diffusion as a metric tensor. The influence of matter to the energy density of the stochastic
Zakir, Zahid
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source