Results 81 to 90 of about 16,306 (215)

Exploring white matter microstructural alterations in mild cognitive impairment: a multimodal diffusion MRI investigation utilizing diffusion kurtosis and free-water imaging

Frontiers in Neuroscience
BackgroundMild Cognitive Impairment (MCI) is a transitional stage from normal aging to dementia, characterized by noticeable changes in cognitive function that do not significantly impact daily life.
Megan R. Nelson, Megan R. Nelson, Elizabeth G. Keeling, Elizabeth G. Keeling, Ashley M. Stokes, Maurizio Bergamino   +5 more
doaj   +1 more source

Enhanced pre-frontal functional-structural networks to support postural control deficits after traumatic brain injury in a pediatric population [PDF]

, 2017
Traumatic brain injury (TBI) affects the structural connectivity, triggering the re-organization of structural-functional circuits in a manner that remains poorly understood.
Bonifazi, Paolo, Cortes, Jesus M, Diez, Ibai, Drijkoningen, David, Gooijers, Jolien, Marinazzo, Daniele, Stramaglia, Sebastiano, Swinnen, Stephan P   +7 more
core   +3 more sources

Effects of diffusional kurtosis imaging parameters on diffusion quantification [PDF]

Radiological Physics and Technology, 2013
Diffusional kurtosis imaging (DKI) is a new technique based on non-Gaussian water diffusion analysis. However, the original DKI protocol (six b values and 30 motion-probing gradient (MPG) directions) requires more than 10 min of scanning time, which is too long for daily clinical use. We aimed to find suitable b value, MPG direction, and diffusion time
Fukunaga, Issei, Hori, Masaaki, Masutani, Yoshitaka, Hamasaki, Nozomi, Sato, Shuji, Suzuki, Yuriko, Kumagai, Fumitaka, Kosuge, Masatsugu, Hoshito, Haruyoshi, Kamagata, Koji, Shimoji, Keigo, Nakanishi, Atsushi, Aoki, Shigeki, Senoo, Atsushi   +13 more
openaire   +2 more sources

Simulation‐Informed Evaluation of Microvascular Parameter Mapping for Diffusion MR Imaging of Solid Tumours

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose We aim to inform the design of new diffusion MRI (dMRI) approaches for microvasculature quantification that enhance the biological specificity of imaging towards cancer. Methods We adopted simulation‐informed modelling of the vascular dMRI signal. We synthesised signals from 1500 synthetic vascular networks, for a variety of protocols (
Anna Kira Voronova, Olivia Prior, Athanasios Grigoriou, Francesc Salvà, Elena Elez, Luz M. Atlagich, Roser Sala‐Llonch, Marco Palombo, Els Fieremans, Dmitry S. Novikov, Raquel Perez‐Lopez, Francesco Grussu   +11 more
wiley   +1 more source

Diffusion kurtosis imaging and conventional diffusion weighted imaging to assess electrochemotherapy response in locally advanced pancreatic cancer

Radiology and Oncology, 2019
The aim of the study was to evaluate diagnostic performance of functional parameters derived by conventional mono-exponential approach of diffusion weighted imaging (DWI) and by diffusion kurtosis imaging (DKI) in the assessment of pancreatic tumours ...
Granata Vincenza, Fusco Roberta, Setola Sergio Venanzio, Palaia Raffaele, Albino Vittorio, Piccirillo Mauro, Grimm Robert, Petrillo Antonella, Izzo Francesco   +8 more
doaj   +1 more source

Assessing Measurement Repeatability of a Novel Anisotropic Phantom for Advanced Diffusion MRI Models

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Diffusion MRI is widely used to characterize tissue microstructure, but standardization remains challenging, particularly for advanced models or regions with crossing fibers. Phantoms provide controlled environments to assess measurement repeatability independent of biological variability.
Lauren Stephens, Sofia Chavez, Fergal Kerins, Michael D. Noseworthy   +3 more
wiley   +1 more source

Diffusion Kurtosis Imaging of Microstructural Changes in Gray Matter Nucleus in Parkinson Disease

Frontiers in Neurology, 2020
Objective: To explore the microstructural damage of extrapyramidal system gray matter nuclei in Parkinson disease (PD) using diffusion kurtosis imaging (DKI).Materials and Methods: We enrolled 35 clinically confirmed PD patients and 23 healthy volunteers.
Gao Bingbing, Zhou Yujing, Miao Yanwei, Dong Chunbo, Wang Weiwei, Tian Shiyun, Liu Yangyingqiu, Shang Jin, Song Qingwei, Liu Ailian, Xie Lizhi   +10 more
doaj   +1 more source

Three-Dimensional Myoarchitecture of the Lower Esophageal Sphincter and Esophageal Hiatus Using Optical Sectioning Microscopy. [PDF]

, 2017
Studies to date have failed to reveal the anatomical counterpart of the lower esophageal sphincter (LES). We assessed the LES and esophageal hiatus morphology using a block containing the human LES and crural diaphragm, serially sectioned at 50 μm ...
Cheng, Leo K, Kumar, Dushyant, Mittal, Ravinder K, Zifan, Ali   +3 more
core   +2 more sources

Characterizing the Diffusion Properties of Prostate Tissue Using Paired MR Microscopy and Multidimensional Diffusion MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To characterize the diffusion properties of prostate epithelium and stroma in benign tissue and cancer. Methods Paired MR microscopy (20 μm) and multidimensional diffusion MRI (dMRI) (160 μm, b = 1000–2000 s/mm2, ∆ = 15–120 ms) were performed at 16.4 T on 17 fixed prostate tissue samples (14× benign, 2× Gleason 3 + 3, 1× Gleason 4 + 4).
Adam Phipps, Nyoman D. Kurniawan, Geoff Watson, Paul Sved, Samson Dowland, Eleftheria Panagiotaki, David Atkinson, Roger Bourne   +7 more
wiley   +1 more source

Diffusion kurtosis imaging for different brain masses characterization

The Egyptian Journal of Radiology and Nuclear Medicine
Background Diffusion kurtosis imaging is an advanced magnetic resonance imaging technique that reveals additional information on the microstructure and micro-dynamics of different brain masses without the need for contrast agents.
Reem M. Abdelnasser, Aya AbdelGaleel, Ahmed H. Farhoud, Yasser Mazloum, M. Ihab Reda   +4 more
doaj   +1 more source