Results 71 to 80 of about 16,306 (215)

Effects of nongaussian diffusion on "isotropic diffusion measurements'': an ex-vivo microimaging and simulation study

, 2019
Designing novel diffusion-weighted pulse sequences to probe tissue microstructure beyond the conventional Stejskal-Tanner family is currently of broad interest.
Ianuş, Andrada, Jespersen, Sune Nørhøj, Olesen, Jonas Lynge, Shemesh, Noam   +3 more
core   +1 more source

Technical advancements and protocol optimization of diffusion-weighted imaging (DWI) in liver [PDF]

, 2016
An area of rapid advancement in abdominal MRI is diffusion-weighted imaging (DWI). By measuring diffusion properties of water molecules, DWI is capable of non-invasively probing tissue properties and physiology at cellular and macromolecular level.
Chen, Ziqian, Lin, Chen, Lin, Yuning, Ni, Ping, Sandrasegaran, Kumar, Zhong, Qun   +5 more
core   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, EarlyView.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Towards Clinical Translation of Intravoxel Incoherent Motion MRI: Acquisition and Analysis Consensus Recommendations

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Intravoxel incoherent motion (IVIM) MRI allows for simultaneous assessment of tissue microcirculation (perfusion) and diffusion of water. In single‐center studies, IVIM has shown great potential for diagnosis, treatment outcome prediction, and treatment monitoring for many different diseases and organs.
Eric E. Sigmund, Susanne S. Rauh, Mami Iima, Christian Federau, Diego Hernando, Oscar Jalnefjord, Jacobus F. A. Jansen, Jonas Jasse, Neil Peter Jerome, Misha P. T. Kaandorp, Sila Kurugol, Frederik B. Laun, Mira M. Liu, Alexandra Ljimani, Thoralf Niendorf, David A. Reiter, Mohammed Salman Shazeeb, Amita Shukla‐Dave, Julia Stabinska, Andreas Wetscherek, Peter T. While, Dan Wu, Denis Le Bihan, Oliver J. Gurney‐Champion   +23 more
wiley   +1 more source

Characterization of white matter alterations using diffusion kurtosis imaging in patients with amyotrophic lateral sclerosis

Brain and Behavior, 2023
Background To evaluate the degeneration of the corticospinal tract (CST) and corpus callosum (CC) in patients with motor neuron disease and upper motor neuron (UMN) dysfunction using diffusion kurtosis imaging (DKI).
Tanushka Anand, Abdullah Ishaque, Daniel Ta, Muhammad Umer Khan, Komal Bharti, Andrew Wu, Dennell Krebs, Christian Beaulieu, Peter Seres, Sanjay Kalra   +9 more
doaj   +1 more source

Whole-lesion histogram analysis of multiple diffusion metrics for differentiating lung cancer from inflammatory lesions

Frontiers in Oncology, 2023
BackgroundWhole-lesion histogram analysis can provide comprehensive assessment of tissues by calculating additional quantitative metrics such as skewness and kurtosis; however, few studies have evaluated its value in the differential diagnosis of lung ...
Jiaxin Li, Baolin Wu, Zhun Huang, Yixiang Zhao, Sen Zhao, Shuaikang Guo, Shufei Xu, Xiaolei Wang, Tiantian Tian, Zhixue Wang, Jun Zhou   +10 more
doaj   +1 more source

Revealing Hidden Potentials of the q-Space Signal in Breast Cancer

, 2017
Mammography screening for early detection of breast lesions currently suffers from high amounts of false positive findings, which result in unnecessary invasive biopsies.
Bickelhaupt, Sebastian, Bonekamp, David, Delorme, Stefan, Heidi, Daniel, Jaeger, Paul, Kuder, Tristan Anselm, Laun, Frederik Bernd, Lederer, Wolfgang, Maier-Hein, Klaus H., Paech, Daniel, Radbruch, Alexander, Schlemmer, Heinz-Peter, Steudle, Franziska   +12 more
core   +1 more source

MRI for Lung Cancer Management: Any Closer to Clinical Application?

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Management of lung cancer (LC) encompasses screening, diagnosis, staging, radiotherapy planning and guidance, therapy monitoring and surveillance. Across these domains, magnetic resonance imaging (MRI) offers a range of morphological and functional imaging capabilities—including diffusion‐weighted imaging (DWI), dynamic contrast‐enhanced (DCE)
Juergen Biederer, Liisa L. Bergmann, Jeanne B. Ackman, Bruno Hochhegger, Lea Azour, Simon M. F. Triphan, Julien Dinkel, Yoshiharu Ohno, Yoshiyuki Ozawa, Edwin J. R. van Beek, Lena Wucherpfennig   +10 more
wiley   +1 more source

White Matter Abnormalities and Cognitive Deficit After Mild Traumatic Brain Injury: Comparing DTI, DKI, and NODDI

Frontiers in Neurology, 2022
White matter (WM) disruption is an important determinant of cognitive impairment after mild traumatic brain injury (mTBI), but traditional diffusion tensor imaging (DTI) shows some limitations in assessing WM damage.
Sihong Huang, Chuxin Huang, Mengjun Li, Huiting Zhang, Jun Liu, Jun Liu, Jun Liu   +6 more
doaj   +1 more source

A two‐stage model for precise identification and Gleason grading of clinically significant prostate cancer: a hybrid approach

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 93-105, March 2025.
This study developed a two‐stage model using radiomics‐based multiparametric MRI and clinical indicators to help identify and grade clinically significant prostate cancer. The model showed promising levels of diagnostic accuracy and predictive performance.
Yuyan Zou, Xuechun Wang, Fen Ma, Xulun Liu, Chunyue Jiao, Zhen Kang, Jingjing Cui, Yang Zhang, Yan Xie, Lei Chen, Ronghua Tian   +10 more
wiley   +1 more source