Results 71 to 80 of about 2,863,637 (184)

Dynamic evolution of microstructure in thalamic subregions of patients with cirrhosis: A study based on diffusion kurtosis imaging

Brain Research Bulletin
Objectives: To investigate the cross-sectional and longitudinal dynamics of the thalamic subregion microstructure in patients with liver cirrhosis by diffusion kurtosis imaging (DKI) and explore its relationship with cognitive function.
Qi Zhang, Zhi-Jing Zhang, Yi-Ning Zhang, Wen-Ting Ma, Xiao-Di Zhang, Zi-Ning Lu, Xiao-Dong Zhang, Wen Shen, Yue Cheng   +8 more
doaj   +1 more source

Intravoxel incoherent motion imaging combined with diffusion kurtosis imaging to assess the response to radiotherapy in a rabbit VX2 malignant bone tumor model

Cancer Imaging, 2022
Purpose To combine intravoxel incoherent motion (IVIM) imaging and diffusion kurtosis imaging (DKI) parameters for the evaluation of radiotherapy response in rabbit VX2 malignant bone tumor model.
Jia Guo, Weikai Sun, Cheng Dong, Zengjie Wu, Xiaoli Li, Ruizhi Zhou, Wenjian Xu   +6 more
doaj   +1 more source

Multimodal MRI and multiomics reveal high‐risk neurophenotype in brain‐gut circuits as therapeutic target for Crohn's disease

Interdisciplinary Medicine, Volume 4, Issue 4, July 2026.
Through a translational framework combining prospective dual‐center clinical cohorts with dextran sulfate sodium‐induced colitis models, this work integrated advanced neuroimaging, multi‐omics and neuromodulation interventions to redefine the high‐risk neurophenotype as a sustained pathogenic driver rather than a mere phenomenon, proposing brain‐gut ...
Xuehua Li, Ruonan Zhang, Xiaodi Shen, Shaochun Lin, Chuhuai Wang, Weikai Zheng, Weimiao Kong, Zihao Lin, Rongchang Li, Caiguang Liu, Xin Cao, Li Huang, Weitao He, Jinjiang Lin, Haijie Wang, Zhoulei Li, Marietta Iacucci, Subrata Ghosh, Zhenpeng Peng, Canhui Sun, Minhu Chen, Guang Yang, Yejun Wang, Ren Mao, Shi‐Ting Feng   +24 more
wiley   +1 more source

Constrained diffusion kurtosis imaging using ternary quartics & MLE

, 2012
International audiencePurpose: Diffusion kurtosis imaging (DKI) is a recent improvement over diffusion tensor imaging that characterizes tissue by quantifying non-gaussian diffusion using a 3D fourth-order kurtosis tensor.
Tristan Milne, Milne, Tristan, Rachid Deriche, Deriche, Rachid, Aurobrata Ghosh, Ghosh, Aurobrata   +5 more
core   +1 more source

Microstructural changes of the white matter in systemic lupus erythematosus patients without neuropsychiatric symptoms: a multi-shell diffusion imaging study

Arthritis Research & Therapy
Background Diffusion kurtosis imaging (DKI) and neurite orientation dispersion and density imaging (NODDI) provide more comprehensive and informative perspective on microstructural alterations of cerebral white matter (WM) than single-shell diffusion ...
Wenjun Hu, Ziru Qiu, Qin Huang, Yuhao Lin, Jiaying Mo, Linhui Wang, Jingyi Wang, Kan Deng, Yanqiu Feng, Xinyuan Zhang, Xiangliang Tan   +10 more
doaj   +1 more source

Assessing Measurement Repeatability of a Novel Anisotropic Phantom for Advanced Diffusion MRI Models

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 339-348, July 2026.
ABSTRACT Purpose Diffusion MRI is widely used to characterize tissue microstructure, but standardization remains challenging, particularly for advanced models or regions with crossing fibers. Phantoms provide controlled environments to assess measurement repeatability independent of biological variability.
Lauren Stephens, Sofia Chavez, Fergal Kerins, Michael D. Noseworthy   +3 more
wiley   +1 more source

Temporal lobe microstructural abnormalities in patients with nasopharyngeal carcinoma quantitatively evaluated by high-resolution DWI and DKI after concurrent chemoradiotherapy

Clinical and Translational Radiation Oncology, 2020
Purpose: To investigate temporal lobe microstructural abnormalities and neurocognitive function impairment after concurrent chemoradiotherapy (CCRT) in patients with nasopharyngeal carcinoma (NPC).
Gang Wu, Rui-rui Li, Priya S. Balasubramanian, Meng-meng Li, Kai Yang, Wei-yuan Huang, Feng Chen   +6 more
doaj   +1 more source

Characterizing the Diffusion Properties of Prostate Tissue Using Paired MR Microscopy and Multidimensional Diffusion MRI

Magnetic Resonance in Medicine, Volume 96, Issue 1, Page 349-365, July 2026.
ABSTRACT Purpose To characterize the diffusion properties of prostate epithelium and stroma in benign tissue and cancer. Methods Paired MR microscopy (20 μm) and multidimensional diffusion MRI (dMRI) (160 μm, b = 1000–2000 s/mm2, ∆ = 15–120 ms) were performed at 16.4 T on 17 fixed prostate tissue samples (14× benign, 2× Gleason 3 + 3, 1× Gleason 4 + 4).
Adam Phipps, Nyoman D. Kurniawan, Geoff Watson, Paul Sved, Samson Dowland, Eleftheria Panagiotaki, David Atkinson, Roger Bourne   +7 more
wiley   +1 more source

Diffusion kurtosis imaging for characterizing tumor heterogeneity in an intracranial rat glioblastoma model [PDF]

, 2020
The utility of diffusion kurtosis imaging (DKI) for assessing intra-tumor heterogeneity was evaluated in a rat model of glioblastoma multiforme. Longitudinal MRI including T2-weighted and diffusion-weighted MRI (DWI) was performed on six female Fischer ...
Clémentine Lesbats, Harish Poptani, Kelly, Claire Louise, Czanner, Gabriela, Lesbats, Clémentine, Poptani, Harish, Gabriela Czanner, Claire Louise Kelly   +7 more
core   +1 more source

Non-invasive identification of KRAS mutation in rectal cancer using hybrid intravoxel incoherent motion and diffusion kurtosis model

World Journal of Surgical Oncology
Background and purpose Sarcoma Viral Oncogene Homologue (KRAS) mutation status is a crucial biomarker in rectal cancer as KRAS mutations confer resistance to anti-EGFR targeted therapies and influence chemotherapy selection, affecting treatment decisions
Jie Yuan, Mingrong Yao, Ziyuan Wang, Wenli Tan, Yun Zhang, Huamei Yan, Mengxiao Liu, Kun Liu, Hangjun Gong, Songhua Zhan   +9 more
doaj   +1 more source