Results 81 to 90 of about 2,863,637 (184)

Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology

Alzheimer’s Research & Therapy, 2018
Background Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia in the elderly population. In this study, we used the APP/PS1 transgenic mouse model to explore the feasibility of using diffusion ...
Jelle Praet, Nikolay V. Manyakov, Leacky Muchene, Zhenhua Mai, Vasilis Terzopoulos, Steve de Backer, An Torremans, Pieter-Jan Guns, Tom Van De Casteele, Astrid Bottelbergs, Bianca Van Broeck, Jan Sijbers, Dirk Smeets, Ziv Shkedy, Luc Bijnens, Darrel J. Pemberton, Mark E. Schmidt, Annemie Van der Linden, Marleen Verhoye   +18 more
doaj   +1 more source

The Role of Dendritic Spines in Water Exchange Measurements With Diffusion MRI: Double Diffusion Encoding and Free‐Waveform MRI

NMR in Biomedicine, Volume 39, Issue 7, July 2026.
Geometric water exchange in dendritic spines imparts a similar signature on diffusion‐MRI signals as permeative, transmembrane water exchange. Current diffusion MRI methods are non‐specific to geometric and permeative exchange. This work proposes a method to disentangle these two modes of exchange, yielding both more accurate estimates of permeative ...
Arthur Chakwizira, Kadir Şimşek, Filip Szczepankiewicz, Marco Palombo, Markus Nilsson   +4 more
wiley   +1 more source

Towards Clinical Translation of Intravoxel Incoherent Motion MRI: Acquisition and Analysis Consensus Recommendations

Journal of Magnetic Resonance Imaging, Volume 63, Issue 6, Page 1782-1801, June 2026.
ABSTRACT Intravoxel incoherent motion (IVIM) MRI allows for simultaneous assessment of tissue microcirculation (perfusion) and diffusion of water. In single‐center studies, IVIM has shown great potential for diagnosis, treatment outcome prediction, and treatment monitoring for many different diseases and organs.
Eric E. Sigmund, Susanne S. Rauh, Mami Iima, Christian Federau, Diego Hernando, Oscar Jalnefjord, Jacobus F. A. Jansen, Jonas Jasse, Neil Peter Jerome, Misha P. T. Kaandorp, Sila Kurugol, Frederik B. Laun, Mira M. Liu, Alexandra Ljimani, Thoralf Niendorf, David A. Reiter, Mohammed Salman Shazeeb, Amita Shukla‐Dave, Julia Stabinska, Andreas Wetscherek, Peter T. While, Dan Wu, Denis Le Bihan, Oliver J. Gurney‐Champion   +23 more
wiley   +1 more source

Diffusion kurtosis imaging

, 2016
: Diffusion kurtosis imaging (DKI) is a recent imaging method that probes the diffusion of water molecules. Whereas diffusion tensor imaging (DTI) models the diffusion as a 3D Gaussian function, DKI takes it one step further by additionally quantifying ...
Veraart, Jelle, Sijbers, Jan
core  

Comparative Evaluation of Diffusion Kurtosis Imaging and Diffusion Tensor Imaging in Detecting Cerebral Microstructural Changes in Alzheimer Disease

, 2021
Comparative evaluation of diffusion kurtosis imaging (DKI) and diffusion tensor imaging (DTI) using a whole-brain atlas to comprehensively evaluate microstructural changes in the brain of Alzheimer disease (AzD) patients. Twenty-seven AzD patients and 25
Vyas, Sameer, Goyal, Manoj K, Kumar, Ajay, Garg, Gaurav, Kamal Ahuja, Chirag, Govind, Varan, Singh, Paramjeet, Modi, Manish, Raj, Shashank   +8 more
core   +1 more source

MRI for Lung Cancer Management: Any Closer to Clinical Application?

Journal of Magnetic Resonance Imaging, Volume 63, Issue 6, Page 1546-1561, June 2026.
ABSTRACT Management of lung cancer (LC) encompasses screening, diagnosis, staging, radiotherapy planning and guidance, therapy monitoring and surveillance. Across these domains, magnetic resonance imaging (MRI) offers a range of morphological and functional imaging capabilities—including diffusion‐weighted imaging (DWI), dynamic contrast‐enhanced (DCE)
Juergen Biederer, Liisa L. Bergmann, Jeanne B. Ackman, Bruno Hochhegger, Lea Azour, Simon M. F. Triphan, Julien Dinkel, Yoshiharu Ohno, Yoshiyuki Ozawa, Edwin J. R. van Beek, Lena Wucherpfennig   +10 more
wiley   +1 more source

MRI Characterization of non-Gaussian water diffusion in the brain using Diffusion Kurtosis Imaging (DKI)

, 2016
Diffusion tensor imaging (DTI) is the most commonly used technique to extract microstructural features from a set of diffusion-weighted images. In addition to the metrics obtained with DTI, diffusion kurtosis imaging (DKI) can provide non-Gaussian ...
COLLURA, Giorgio, GAGLIARDO, Cesare, NICI, STEFANIA, GALLO, Salvatore, MARRALE, Maurizio   +4 more
core  

Joint diffusional kurtosis magnetic resonance imaging analysis of white matter and the thalamus to identify subcortical ischemic vascular disease

Scientific Reports
Identifying subcortical ischemic vascular disease (SIVD) in older adults is important but challenging. Growing evidence suggests that diffusional kurtosis imaging (DKI) can detect SIVD-relevant microstructural pathology, and a systematic assessment of ...
Min-Chien Tu, Sheng-Min Huang, Yen-Hsuan Hsu, Jir-Jei Yang, Chien-Yuan Lin, Li-Wei Kuo   +5 more
doaj   +1 more source

Complementary Sensitivity of Fixed‐Time and Fixed‐Oscillation Regimes to Exchange and Structural Disorder in the Human Brain Revealed Using Oscillating‐Gradient Diffusion MRI With Ultra‐Strong Gradients

Magnetic Resonance in Medicine, Volume 95, Issue 6, Page 3429-3444, June 2026.
ABSTRACT Purpose Oscillating‐gradient spin‐echo (OGSE) diffusion MRI probes cell geometry and membrane integrity through the frequency‐dependence of kurtosis, but prior studies have reported inconsistent findings depending on how frequency is varied. We compared frequency‐dependent kurtosis in the human brain under two regimes: varying frequency with ...
Dongsuk Sung, Kwok‐Shing Chan, Julianna Gerold, Wen Zhong, Jialan Zheng, Qiyuan Tian, Hua Guo, Susie Y. Huang, Hong‐Hsi Lee   +8 more
wiley   +1 more source

Diffusion kurtosis imaging of white matter in bipolar disorder

, 2021
White matter pathology likely contributes to the pathogenesis of bipolar disorder (BD). Most studies of white matter in BD have used diffusion tensor imaging (DTI), but the advent of more advanced multi-shell diffusion MRI imaging offers the possibility ...
Shakeel, Mohammed K, David, Szabolcs, Emsell, Louise, De Luca, Alberto, Beasley, Clare, Goghari, Vina M, Kusi, Mavis, Leemans, Alexander   +7 more
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