Results 51 to 60 of about 4,757,811 (304)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Relationship between timed 25-foot walk and diffusion tensor imaging in multiple sclerosis

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2016
Objective/Background The majority of multiple sclerosis patients experience impaired walking ability, which impacts quality of life. Timed 25-foot walk is commonly used to gauge gait impairment but results can be broadly variable.
Sylvia Klineova, Rebecca Farber, Catarina Saiote, Colleen Farrell, Bradley N Delman, Lawrence N Tanenbaum, Joshua Friedman, Matilde Inglese, Fred D Lublin, Stephen Krieger   +9 more
doaj   +1 more source

LOW AND MEAN RADIATION DOSES IMPACT ON THE CEREBRAL TRACTS STRUCTURE OF THE CHERNOBYL ACCIDENT LIQUIDATORS IN THE REMOTE PERIOD (BASED ON ROUTINE AND DIFFUSION-TENSOR MAGNETIC RESONANCE IMAGING DATA)

Радиационная гигиена, 2018
To evaluate correlation between brain structural damages and radiation exposure level for the Chernobyl nuclear power plant accident liquidators, routine and diffusion tensor magnetic resonance imaging methods are efficient to visualize and evaluate ...
I. M. Levashkina, S. S. Aleksanin, S. V. Serebryakova, T. G. Gribanova   +3 more
doaj   +1 more source

Imaging in population science: cardiovascular magnetic resonance in 100,000 participants of UK Biobank - rationale, challenges and approaches. [PDF]

, 2013
UK Biobank is a prospective cohort study with 500,000 participants aged 40 to 69. Recently an enhanced imaging study received funding. Cardiovascular magnetic resonance (CMR) will be part of a multi-organ, multi-modality imaging visit in 3-4 dedicated UK
Frank E Rademakers, Steffen E Petersen, Petersen, SE, Rademakers, Frank E., Neubauer, Stefan, Nagel, E, Peakman, T, Sellors, J, Peakman, Tim, Petersen, Steffen E., Rademakers, Frank E, Rademakers, FE, Paul Leeson, Nagel, Eike, Matthews, PM, Young, AA, Tim Peakman, Fabian Bamberg, Plein, S, Friedrich, MG, Young, Alistair A, Steve Garratt, Jane M Francis, Sven Plein, Francis, Jane M., Rory Collins, Friedrich, Matthias G, Plein, Sven, Bluemke, David A., Young, Alistair A., Alistair A Young, Jonathan Sellors, Collins, Rory, Leeson, Paul, Francis, JM, Bamberg, F, David A Bluemke, Collins, R, Francis, Jane M, Garratt, Steve, Paul M Matthews, Bluemke, David A, Matthews, Paul M, Matthias G Friedrich, Friedrich, Matthias G., Sellors, Jonathan, Bluemke, DA, Garratt, S, Matthews, Paul M., Neubauer, S, Bamberg, Fabian, Petersen, Steffen E, Eike Nagel, Stefan Neubauer, Leeson, P   +54 more
core   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Rim Sign in Breast Lesions on Diffusion-Weighted Magnetic Resonance Imaging: Diagnostic Accuracy and Clinical Usefulness

, 2015
PurposeTo investigate the diagnostic accuracy and clinical usefulness of the rim sign in breast lesions observed in diffusion-weighted magnetic resonance imaging (DWI).
Kang, Bong Joo, Ikeda, Debra M., Moran, Catherine J., Bruce Lewis Daniel, Jafi Alyssa Lipson, Planey, Katie RoseMary, Catherine J. Moran, Katie RoseMary Planey, Jennifer Kao, Debra M. Ikeda, Zackrisson, Sophia,, Pal, Sunita, Daniel, Bruce Lewis, Bong Joo Kang, Zackrisson, Sophia, Kao, Jennifer, Sophia Zackrisson, Sunita Pal, Lund University., Lipson, Jafi Alyssa   +19 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Pre- and post-surgery brain tumor multimodal magnetic resonance imaging data optimized for large scale computational modelling

Scientific Data, 2022
Measurement(s) BOLD signal • Diffusion Anisotropy Technology Type(s) Functional Magnetic Resonance Imaging • Diffusion Weighted Imaging Factor Type(s) Surgery Sample Characteristic - Organism Homo ...
Hannelore Aerts, Nigel Colenbier, Hannes Almgren, Thijs Dhollander, Javier Rasero Daparte, Kenzo Clauw, Amogh Johri, Jil Meier, Jessica Palmer, Michael Schirner, Petra Ritter, Daniele Marinazzo   +11 more
doaj   +1 more source

Gelatinous Transformation of Bone Marrow Mimicking Malignant Marrow-Replacing Lesion on Magnetic Resonance Imaging in a Patient without Underlying Devastating Disease [PDF]

, 2018
Gelatinous transformation of bone marrow is characterized by hypoplasia of fat cells with focal loss of hematopoietic cells and deposition of extracellular gelatinous substances.
유연화, 이주희, 김성준, 김학선   +3 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source