Results 61 to 70 of about 26,340 (261)

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Relationship between timed 25-foot walk and diffusion tensor imaging in multiple sclerosis

Multiple Sclerosis Journal - Experimental, Translational and Clinical, 2016
Objective/Background The majority of multiple sclerosis patients experience impaired walking ability, which impacts quality of life. Timed 25-foot walk is commonly used to gauge gait impairment but results can be broadly variable.
Sylvia Klineova, Rebecca Farber, Catarina Saiote, Colleen Farrell, Bradley N Delman, Lawrence N Tanenbaum, Joshua Friedman, Matilde Inglese, Fred D Lublin, Stephen Krieger   +9 more
doaj   +1 more source

LOW AND MEAN RADIATION DOSES IMPACT ON THE CEREBRAL TRACTS STRUCTURE OF THE CHERNOBYL ACCIDENT LIQUIDATORS IN THE REMOTE PERIOD (BASED ON ROUTINE AND DIFFUSION-TENSOR MAGNETIC RESONANCE IMAGING DATA)

Радиационная гигиена, 2018
To evaluate correlation between brain structural damages and radiation exposure level for the Chernobyl nuclear power plant accident liquidators, routine and diffusion tensor magnetic resonance imaging methods are efficient to visualize and evaluate ...
I. M. Levashkina, S. S. Aleksanin, S. V. Serebryakova, T. G. Gribanova   +3 more
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

A method for improving the performance of gradient systems for diffusion-weighted MRI

, 2007
The MR signal is sensitive to diffusion. This effect can be increased by the use of large, balanced bipolar gradients. The gradient systems of MR scanners are calibrated at installation and during regular servicing visits.
Daniel C. Alex, Zoltan Nagy, Ralf Deichmann, Weiskopf, N. ; https://orcid.org/, Alexander, D., Nagy, Z., Nagy, Zoltan, Deichmann, R., Alexander, Daniel C., Weiskopf, Nikolaus, Deichmann, Ralf, Nikolaus Weiskopf   +11 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Diffusion-sensitive magnetic resonance spectroscopy and imaging in biomedical sciences

, 2013
We present a mini-review of the development and contemporary applications of diffusion-sensitive\ud nuclear magnetic resonance (NMR) techniques in biomedical sciences.
Momot, Konstantin I.
core   +1 more source

Diffusion tensor magnetic resonance imaging and fiber tractography of the sacral plexusin children with spina bifida [PDF]

, 2014
Purpose It is still largely unknown how neural tube defects in spina bifida affect the nerves at the level of the sacral plexus. Visualizing the sacral plexus in 3 dimensions could improve our anatomical understanding of neurological problems in patients
De Jong, T.P.V.M., Dik, P., ten Haken, Bernard, Froeling, M., Nievelstein, R.A.J., Haakma, W., Cuppen, I., Leemans, A.   +7 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source