Results 81 to 90 of about 4,757,811 (304)

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Magnetic resonance imaging of subcutaneous diffuse neurofibroma.

The British Journal of Radiology, 1997
A 31-year-old woman presented with increasing pain and tenderness of a long-standing soft tissue mass on her back. MRI showed a network of interconnecting tubular areas, which were T1 isointense and T2 hyperintense relative to skeletal muscle, and displayed marked Gd-DTPA enhancement. The lesion was situated within the subcutaneous fat.
Peh, WCG, Shek, TWH, Yip, DKH
openaire   +3 more sources

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Diffusion magnetic resonance imaging of chest tumors [PDF]

Cancer Imaging, 2012
This review provides an overview of the current status of the published data on diffusion magnetic resonance (MR) imaging of chest tumors. Diffusion MR imaging is a non-invasive imaging technique that measures the differences in water mobility in different tissue microstructures and quantifies them based on the apparent diffusion coefficient. Diffusion
openaire   +2 more sources

Scedosporium apiospermum endophthalmitis: diffusion-weighted imaging in detecting subchoroidal abscess

Clinical Ophthalmology, 2012
Sandeep Bhuta, Charlie Chia-Tsong Hsu, Gigi Nga Chi KwanGriffith University, School of Medicine, Department of Medical Imaging, Gold Coast Hospital, Southport, Gold Coast, QLD, AustraliaPurpose: To describe the imaging appearance of Scedosporium ...
Kwan GN, Hsu CC, Bhuta S
doaj  

High-resolution diffusion imaging using phase-corrected segmented echo-planar imaging

, 2000
Diffusion magnetic resonance imaging (MRI) was performed with a high-resolution segmented echo-planar imaging technique, which provided images with substantially less susceptibility artifacts than images obtained with single-shot echo-planar imaging (EPI)
Holtås, Stig, Moore, J R, Thomsen, C, Ståhlberg, Freddy, Brockstedt, Sara, Ståhlberg, Freddy,, Brockstedt, Sara,, Holtås, Stig,, Lund University., James R Moore, Sara Brockstedt, Stig Holtås, Freddy Ståhlberg, Carsten Thomsen   +13 more
core   +1 more source

Cardiovascular magnetic resonance activity in the United Kingdom: a survey on behalf of the british society of cardiovascular magnetic resonance [PDF]

, 2011
<p>Background: The indications, complexity and capabilities of cardiovascular magnetic resonance (CMR) have rapidly expanded. Whether actual service provision and training have developed in parallel is unknown.</p> <p>Methods: We ...
J. Moon (6723125), Pennell, D.J., S. Neubauer (1410220), Payne, J., J. Payne (2409088), Antony Renjith, Dargie, HJ, G. P. McCann (7591697), Antony, R, Hawkins, N.M., Payne John, C. Berry (7606274), Dargie, H.J., Renjith Antony, Nathaniel M Hawkins, Henry J Dargie, James Moon, Petrie Mark C, S. Daghem (7606259), Gerry P. McCann (7241615), Moon, J., Daghem, M., Pennell, DJ, Pennell Dudley J, Mark C Petrie, H. J. Dargie (7606265), Neubauer Stefan, Marwa Daghem, Antony, R., Gerry P McCann, R. Antony (7606253), McCann, GP, M. Daghem (7606256), Petrie, M.C., Moon James, Hawkins, NM, Safa Daghem, Daghem Marwa, Berry Colin, Colin Berry, D. J. Pennell (7606268), Dargie Henry J, McCann, G.P., Daghem, S, Payne, J, Neubauer, S., Hawkins Nathaniel M, Daghem, M, Daghem, S., Petrie, MC, McCann Gerry P, N. M. Hawkins (7606271), Moon, J, Dudley J Pennell, Berry, C, Berry, C., Neubauer, S, John Payne, M. C. Petrie (7606262), Daghem Safa, Stefan Neubauer   +60 more
core   +1 more source

Posterior Disconnection Syndrome in Early‐Stage Adult‐Onset Cerebral Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adult‐onset cerebral adrenoleukodystrophy is potentially treatable but often difficult to recognize before advanced cerebral involvement. Herein, we describe three men with early‐stage disease who initially presented with subtle visual complaints rather than subcortical dementia. Targeted neuropsychological testing revealed higher‐order visual
Kazuto Katsuse, Takashi Matsukawa, Yumiko Nakamura, Kazuo Kakinuma, Shoko Ota, Ryo Hara, Saki Nakashima, Kaoru Ito, Yutaro Nakamori, Toshiyuki Kakumoto, Masashi Hamada, Shigenori Kanno, Kyoko Suzuki, Tatsushi Toda   +13 more
wiley   +1 more source

White Matter and Perivascular Imaging Changes in Alzheimer's Disease and Cerebral Amyloid Angiopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peak‐width of skeletonized mean diffusivity (PSMD) and diffusion tensor imaging–analysis along the perivascular space (DTI‐ALPS), reflecting white matter integrity and glymphatic function, are altered in Alzheimer's disease (AD).
Debina Laishram, Guangwei Du, Sangam Kanekar, Nandakumar Nagaraja   +3 more
wiley   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato, Alessia Giugno, Miriam Sturniolo, Enrico Fratto, Pio Zoleo, Francesca Felicia Operto, Ilaria Sammarra, Antonio Gambardella   +7 more
wiley   +1 more source