Results 71 to 80 of about 26,340 (261)

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Rim Sign in Breast Lesions on Diffusion-Weighted Magnetic Resonance Imaging: Diagnostic Accuracy and Clinical Usefulness

, 2015
PurposeTo investigate the diagnostic accuracy and clinical usefulness of the rim sign in breast lesions observed in diffusion-weighted magnetic resonance imaging (DWI).
Kang, Bong Joo, Ikeda, Debra M., Moran, Catherine J., Bruce Lewis Daniel, Jafi Alyssa Lipson, Planey, Katie RoseMary, Catherine J. Moran, Katie RoseMary Planey, Jennifer Kao, Debra M. Ikeda, Zackrisson, Sophia,, Pal, Sunita, Daniel, Bruce Lewis, Bong Joo Kang, Zackrisson, Sophia, Kao, Jennifer, Sophia Zackrisson, Sunita Pal, Lund University., Lipson, Jafi Alyssa   +19 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

MRI texture analysis as means for addressing rehydration and milk diffusion in cereals

, 2011
Cereals microstructure is one of the primary quality attributes of cereals. Cereals rehydration and milk diffusion depends on such microstructure and thus, the crispiness and the texture, which will make it more palatable for the final consumer. Magnetic
Rodríguez Sinobas, Leonor, Fernandez Valle, M. Encarnacion, Melado Herreros, Angela, Chassagne-Berces, Sophie, Fernández-Valle, María Encarnación, Ruiz Cabello Osuna, Jesus Maria, Chanvrier, Helene, Barreiro, Pilar, Melado, Angela, Ruíz-Cabello, Jesús, Barreiro Elorza, Pilar, Rodríguez-Sinobas, Leonor   +11 more
core   +1 more source

Dopamine restores reward prediction errors in old age [PDF]

, 2013
Senescence affects the ability to utilize information about the likelihood of rewards for optimal decision-making. Using functional magnetic resonance imaging in humans, we found that healthy older adults had an abnormal signature of expected value ...
Dayan, P., Dolan, Raymond J, Dayan, P, Dolan, R., Huys, Q., Guitart-Masip, M. ; https://orcid.org/, Düzel, E., Rumana Chowdhury, Chowdhury, R., Christian Lambert, Emrah Düzel, Duezel, Emrah, Guitart-Masip, M., Dolan, Raymond J., Lambert, C., Lambert, C, Chowdhury, Rumana, Chowdhury, R, Guitart-Masip, Marc,, Guitart-Masip, Marc, Dolan, RJ, Marc Guitart-masip, Düzel, E, Dolan, R. ; https://orcid.org/, Raymond J Dolan, Peter Dayan, Dayan, Peter, Guitart-Masip, M, Düzel, Emrah, Huys, Q, Lambert, Christian, Quentin Huys, Huys, Quentin   +32 more
core   +1 more source

Remarkable Recovery After Delayed High‐Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Traumatic spinal cord injury (TSCI) caused by sharp‐force penetration is exceptionally rare, and the use of high‐dose methylprednisolone (MP) remains highly controversial, especially beyond the conventional 8‐h treatment window. This case report describes a 30‐year‐old male with acute incomplete TSCI following a knife stab wound to the right ...
Honghong Wang, Shuang Liu, Jiale Wang, Kaiyang Xue, Shenwei Li, Zhongheng Du   +5 more
wiley   +1 more source

Fiber tracking in q-ball fields using regularized particle trajectories [PDF]

, 2005
Most of the approaches dedicated to fiber tracking from diffusion-weighted MR data rely on a tensor model. However, the tensor model can only resolve a single fiber orientation within each imaging voxel.
Le Bihan, D, Cointepas, Y., Golestani, N, Constantinesco, A, D. Rivière, Cointepas, Y, A. Constantinesco, Poupon, C., C. Pallier, J. -F. Mangin, Y. Cointepas, Perrin, M, Riviere, D, Constantinesco, A., Perrin, M., D. Le Bihan, M. Perrin, Rieul, B, Golestani, N., Pallier, C., Rieul, B., Mangin, J. F., B. Rieul, Le Bihan, D., C. Poupon, N. Golestani, Mangin, JF, Rivière, D., Pallier, C, Poupon, C   +29 more
core   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers, Yaqiao Wei, Dinesh K. Deelchand, Adam Berrington, Young Woo Park, Guita Banan, Michal Povazan, Jens T. Rosenberg, André J. W. van der Kouwe, Tetsuo Ashizawa, Khalaf O. Bushara, Chiadi U. Onyike, Sub H. Subramony, Jeremy D. Schmahmann, Brian J. Soher, Peter B. Barker, Thomas H. Mareci, Eva‐Maria Ratai, Lynn E. Eberly, Gülin Öz   +19 more
wiley   +1 more source