Results 131 to 140 of about 8,073,665 (296)
Diffusion of urea through membranes [PDF]
, 2006 Non-invasive real time monitoring of topical drug delivery is an important subject of dermatopharmaceutical research. It has been proved that Fourier transform infrared attenuated total refection (FTIR-ATR) is a versatile technique to study drug ...
Neubert, Reinhard +3 more
core +1 more source
Reaction-Diffusion in Co2Si/Zn Diffusion Couple
Periodic layered structures were examined in the Co₂Si/Zn diffusion couple annealed at 390 °C. SEM, TEM, EPMA, and XRD analyses revealed alternating Co–Si–rich and Zn–rich layers composed of CoSi, γ₁, and γ₂ phases with cell-to-cell variations in ...
Cserháti, Csaba +4 more
core +1 more source
Using generative AI to transform peptide hits into small molecule leads
Beilstein Journal of Organic ChemistryThere is a wealth of structural data on peptides that bind potential drug targets, serving as rich inspiration for designing small molecule inhibitors which can recapitulate key binding interactions while improving pharmacokinetic properties.
Joshua Mills, Yu Heng Lau
doaj +1 more source
SceneDiffusion: Scene Generation Model Embedded with Spatial Constraints
ISPRS International Journal of Geo-InformationSpatial scenes, as fundamental units of geospatial cognition, encompass rich objects and spatial relationships, and their generation techniques hold significant application value in disaster simulation and emergency drills, delayed spatial reconstruction
Shanshan Yu +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Diffusion Models With Implicit Conditions Driven by Latent Shifts
IEEE AccessThis paper introduces a diffusion model that replaces the target prior distribution from a standard Gaussian to non-zero-mean Gaussian priors, with shifted latent trajectories determined by non-zero-mean Gaussian noise, thereby maintaining the closed ...
Da Eun Lee +2 more
doaj +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
LightEdit: Textual Image Editing With Lightweight Stable Diffusion
IEEE AccessText-based image editing using diffusion models has shown remarkable progress, but most approaches rely on large-scale models (Stable Diffusion Models - SDMs) that require significant computational resources.
Thuy Phuong Vu +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source