Results 141 to 150 of about 486,752 (312)
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
Although optical remote sensing imagery has been extensively used in various Earth observation tasks, its practical utility is frequently compromised by cloud cover and adverse weather, which lead to missing data and disrupt the temporal continuity of ...
Peizhen Yang +4 more
doaj +1 more source
A fractal based model of diffusion MRI in cortical grey matter
Diffusion Weighted Magnetic Resonance (DWMR) Imaging is an important tool in diagnostic neuroimaging, but the biophysical basis of the DWMR signal from biological tissue is not entirely understood. Testable, theoretical models relating the DWMR signal to
Hansen, Brian +2 more
core
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Multivariate time series anomaly detection holds critical application value in key domains such as industrial system monitoring, financial risk management, and medical surveillance.
Kuo Wu +6 more
doaj +1 more source
ESTIMATING SINGLE FACTOR JUMP DIFFUSION INTEREST RATE MODELS [PDF]
Recent empirical studies have demonstrated that behaviour of interest rate processes can be better explained if standard diffusion processes are augmented with jumps in the interest rate process.
Ghulam Sorwar
core
Continuum diffusion models are often used to represent the collective motion of cell populations. Most previous studies have simply used linear diffusion to represent collective cell spreading, while others found that degenerate nonlinear diffusion ...
McCue, S. W. +11 more
core +1 more source
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Modelling of Innovation Diffusion
Since the publication of the Bass model in 1969, research on the modelling of the diffusion of innovation resulted in a vast body of scientific literature consisting of articles, books, and studies of real-world applications of this model. The main objective of the diffusion model is to describe a pattern of spread of innovation among potential ...
Kijek, Arkadiusz, Kijek, Tomasz
openaire +2 more sources
Missing data are a persistent challenge in large healthcare datasets, often undermining both statistical validity and machine learning performance when handled using simplistic assumptions. In this work, we examine how entropy-based diagnostics can guide
Deepa Fernandes Prabhu +2 more
doaj +1 more source

