Results 91 to 100 of about 1,453,083 (343)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Diffusion processes through social groups' dynamics

open access: yes, 2011
Axelrod's model describes the dissemination of a set of cultural traits in a society constituted by individual agents. In a social context, nevertheless, individual choices toward a specific attitude are also at the basis of the formation of communities,
Apolloni, Andrea, Gargiulo, Floriana
core   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Computer-Aided Design in Electromagnetics - the Case for Surface Impedance Boundary Conditions

open access: yesAdvances in Electrical and Computer Engineering, 2012
Surface impedance boundary conditions (SIBCs) have been successfully used for over 70 years in both analytical and numerical computation. With the need to model increasingly complex geometries and smaller artifacts, its importance in computer-aided ...
IDA, N., Di RIENZO, L., YUFEREV, S.
doaj   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Annihilation-diffusion processes: an exactly solvable model

open access: yes, 2000
A family of diffusion-annihilation processes is introduced, which is exactly solvable. This family contains parameters that control the diffusion- and annihilation- rates. The solution is based on the Bethe ansatz and using special boundary conditions to
Alimohammadi   +13 more
core   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Modern Paradigm of Secured Management of the Development of Complex Hierarchical Systems [PDF]

open access: yesProblemi Ekonomiki
The restructuring of the national economy, the processes of transformation taking place in it, actualize the problems of controlled vector development of complex hierarchical systems in the economy. The purpose of this study is to analyze the theoretical
Serhiienko Olena A.   +3 more
doaj   +1 more source

Extreme value distributions of noncolliding diffusion processes [PDF]

open access: yes, 2010
Noncolliding diffusion processes reported in the present paper are $N$-particle systems of diffusion processes in one-dimension, which are conditioned so that all particles start from the origin and never collide with each other in a finite time interval
Izumi, Minami, Katori, Makoto
core   +2 more sources

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