Results 41 to 50 of about 61,892 (267)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Diffusion on diffusing particles
Diffusion Fundamentals, 2007 We investigate random walk of a particle constrained on cells, where cells behave as a lattice gas on a two dimensional square lattice. By Monte Carlo simulation, we obtain the mean first passage time of the particle as a function of the density and temperature of the lattice gas. We find that the transportation of the particle becomes anomalously slow
Imoto, Yu, Odagaki, Takashi
openaire +2 more sources
From the diffusion coefficient to the diffusion tensor [PDF]
NMR in Biomedicine, 2002 AbstractWith diffusion tensor MRI one has access to the organization in space of tissue microstructural components. This outstanding potential adds, however, another layer of complexity to the diffusion MRI data acquisition and analysis processes. Over the last few years many articles have been published dealing with those matters.
Le Bihan, Denis, van Zijl, Peter
openaire +3 more sources
Diffusion and quantification of diffusion of prostate cancer
The British Journal of Radiology, 2021 For assessing a cancer treatment, and for detecting and characterizing cancer, Diffusion-weighted imaging (DWI) is commonly used. The key in DWI’s use extracranially has been due to the emergence of of high-gradient amplitude and multichannel coils, parallelimaging, and echo-planar imaging.
Yoshiko, Ueno +3 more
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FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
On the diffusion of metals [PDF]
The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science, 1896 n ...
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Геодинамика и тектонофизика, 2015 The 2008 Wenchuan MS8.0 earthquake occurred on Longmenshan fault zone (LMSF), which is at the eastern margin of the Tibetan plateau. The epicenter is near the Shuimogou earthquake swarm, which was thought to be triggered by the Zipingpu reservoir after ...
Liu Yuanzheng, Ma Jin, Jiang Tong
doaj +1 more source
Dissolution of Magnesia in Silicate Melts and Diffusivity Determination from CLSM Studies
Applied Sciences, 2023 Magnesia is one of the vital and extensively used refractory components. In this study, the dissolution of magnesia is investigated at 1450, 1500, and 1550 °C in three silicate slags in the CaO–Al2O3–SiO2–MgO system using high-temperature confocal laser ...
Burhanuddin, Harald Harmuth
doaj +1 more source