Results 101 to 110 of about 724,678 (237)
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Potencial de biodigestores para el tratamiento de efluentes orgánicos en el ámbito rural
Revista de la Sociedad Científica del Paraguay, 2016 El agua es un elemento esencial para la vida y uno de los recursos naturales más valiosos, es por ello, que hoy día, la utilización racional del agua es una preocupación a nivel mundial; a pesar de ello, este recurso, es cada vez más escaso, ya que tanto
Federico Vargas Lehner
doaj
En este documento se presentan diferentes tecnologías utilizadas para la digestión anaerobia en biodigestores, lo que te permitirá comprender las variables importantes en el ...
Huertas Cardozo, José I. +3 more
core
Digestión anaerobia de residuos de biomasa para la producción de biogás. Fundamentos [PDF]
, 2016 En este artículo vamos a presentar los fundamentos de la digestión anaerobia, particularizando en la mezcla de diversas materias primas o codigestión de residuos ganaderos, agrícolas y agroindustriales. Este proceso genera dos subproductos que pueden ser
Palau C.V.
core
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Digestión anaerobia en comunidades rurales [PDF]
, 2008 El objetivo del presente trabajo es de analizar el proceso de digestión anaerobia como mecanismo para la producción de energía mediante el biogás (que tiene un apreciable contenido de metano, elemento necesario para que se utilice como combustible), y en
Torre Caritas, Nadia de la
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Fruit and vegetable residues (HR) represent sustainable and renewable resources that could be valorized in different applications providing alternatives thanks to the availability, high content of polysaccharides, micronutrients and moisture.
Moreno Rocha, Christian Manuel +2 more
core +1 more source