Results 211 to 220 of about 18,251 (262)

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Meeting the estimated daily optimal standardized ileal digestible lysine-to-net energy ratios for first and second parity lactating sows improved piglet growth rates. [PDF]

Transl Anim Sci
Gregory NL, Huber LA.
europepmc   +1 more source

High-moisture extrusion enhances soy protein quality based on in vitro protein digestibility and amino acid scores

Jolien de Boer, Edoardo Capuano, Jannigje G. Kers, Atze Jan van der Goot   +3 more
openalex   +1 more source

Effect of amino acid deficiency on precaecal amino acid digestibility in broiler chickens

, 2019
W. Siegert, Christian Ganzer, H. Kluth, M. Rodehutscord   +3 more
openalex   +2 more sources

FBXO44 Regulates FOXP1 Degradation Through AURKA‐Dependent Phosphorylation to Promote Colorectal Cancer Progression

Advanced Science, EarlyView.
FBXO44 promotes colorectal cancer progression by targeting FOXP1 for ubiquitin‐mediated degradation. This study reveals a phosphorylation‐dependent mechanism involving AURKA and highlights the FBXO44/FOXP1/Cyclin E2 axis as a potential therapeutic target in colorectal cancer.
Hongxu Nie, Hengjie Xu, Sheng Yang, Chuanxin Tian, Tuo Wang, Chi Jin, Zhihao Chen, Xiaowei Wang, Junwei Tang, Yifei Feng, Yueming Sun   +10 more
wiley   +1 more source

Standardized Amino Acid Digestibility Estimates of Individual Ingredients from Precision-Fed Cecectomized Roosters Are Additive. [PDF]

Animals (Basel)
Smola MA, Utterback PL, Parsons CM, Swanson KS.   +3 more
europepmc   +1 more source

Influence of guanidination on apparent ileal amino acid digestibility in some protein sources for broilers

, 1998
V. Ravindran, L. I. Hew, W. L. Bryden
openalex   +1 more source

Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5

Advanced Science, EarlyView.
Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao, Yuan Fei Li, Fu Kang Yuan, Meng Lu Zhao, Ya Wen Han, Jia Xin Wang, Qi Yang, Han Ying Ye, Yu Cheng Lu, Shao Chin Lee   +9 more
wiley   +1 more source

Determination of Digestible Indispensable Amino Acid Scores for Plant Proteins and Skim Milk Powder Measured in Pigs. [PDF]

Animals (Basel)
Oh J, Park N, Kim BG.
europepmc   +1 more source

Skullcapflavone II Inhibits SLC1A4‐Mediated L‐Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer

Advanced Science, EarlyView.
Skullcapflavone II (SkII) significantly alters serine metabolism in gastric cancer cells by directly targeting the L‐serine transporter SLC1A4, thereby inhibiting L‐serine uptake rather than de novo synthesis. This disruption of serine metabolism by SkII leads to increased oxidative stress and consequent mitochondrial damage.
Jing Zhao, Yu‐Bo Ma, Rui‐Hong Xia, Zheng‐Chen Jiang, Ying Zhou, Ya‐Nan Wang, Meng‐Yan Yang, Jing‐Jie Dai, Tao Zhu, Li‐Bin Pan, Li Yuan   +10 more
wiley   +1 more source