Results 91 to 100 of about 674,665 (225)

Microporous Microgel Assemblies Facilitating the Recruitment and Osteogenic Differentiation of Progenitor Cells for Bone Regeneration

Advanced Functional Materials, EarlyView.
There is a significant need for biomaterials with well‐defined stability and bioactivity to support tissue regeneration. In this study, we developed a tunable microgel platform that enables the decoupling of stiffness from porosity, thereby promoting bone regeneration.
Silvia Pravato, Haishuo Guan, Bianca M. Carrara, Mira Jacobs, Matteo Monticelli, Lukas Moser, Thomas Moragues, Andrew J. deMello, Tomaso Zambelli, Martin Ehrbar   +9 more
wiley   +1 more source

Transplacental Antibody Transfer: Mechanisms, Pregnancy-Related Disruptions, and Emerging Experimental Models

Antibodies
The transplacental transfer of maternal immunoglobulin G from the mother to the foetus is central for providing immunity in early life, resulting in full-term newborns having IgG repertoires and levels similar to those of their mothers.
Qiqi Li, Zhengyuan Huang, Zainab Saeed, Orene Greer, James A. Harker, Nishel M. Shah   +5 more
doaj   +1 more source

A Termite‐Inspired Alternative to Cement

Advanced Functional Materials, EarlyView.
A termite‐inspired composite of clay, cellulose, and lignin forms a dense fibrous network with concrete‐like strength (32 MPa) and superior elasticity, processed at ambient temperature. Abstract Clay combined with organic materials is used by termites as a strong and durable construction material for their mounds with minimal environmental impact. Here,
Oren Regev, Peter Fratzl, Emeline Raguin, Markus Antonietti   +3 more
wiley   +1 more source

Clinical application of pre-rehabilitation concept on comfort colonoscopy in Chinese elderly patients: a randomised controlled trial

BMC Gastroenterology
Background The concept of pre-rehabilitation has been clinically implemented across various surgical fields; however, studies investigating its application in colonoscopy remain limited. This study aimed to evaluate the effectiveness, safety, and patient
Lun Zhang, Xiaoling Lv, Qin Zhu, Jianying Zhou, Hanlei Huang, Yiqian Huang, Caijuan Si   +6 more
doaj   +1 more source

Emergent Spin‐Glass Behavior in an Iron(II)‐Based Metal–Organic Framework Glass

Advanced Functional Materials, EarlyView.
A one‐pot, solvent‐free synthesis yields an Fe2+‐based metal‐organic framework (MOF) glass featuring a continuous random network structure. The material exhibits spin‐glass freezing at 14 K, driven by topological‐disorder and short‐range magnetic frustration, showcasing the potential of MOF glasses as a plattform for cooperative magnetic phenomena in ...
Chinmoy Das, Soma Salamon, Joachim Landers, Jan‐Benedikt Weiß, Wen‐Long Xue, Pascal Kolodzeiski, Roman Pallach, Heiko Wende, Sebastian Henke   +8 more
wiley   +1 more source

MAGqual: a stand-alone pipeline to assess the quality of metagenome-assembled genomes

Microbiome
Background Metagenomics, the whole genome sequencing of microbial communities, has provided insight into complex ecosystems. It has facilitated the discovery of novel microorganisms, explained community interactions and found applications in various ...
Annabel Cansdale, James P. J. Chong
doaj   +1 more source

Chemoselective Sequential Polymerization: An Approach Toward Mixed Plastic Waste Recycling

Advanced Functional Materials, EarlyView.
Inspired by biological protein metabolism, this study demonstrates the closed‐loop recycling of mixed synthetic polymers via ring‐closing depolymerization followed by a chemoselective sequential polymerizations process. The approach recovers pure polymers from mixed feedstocks, even in multilayer formats, highlighting a promising strategy to overcome a
Gadi Slor, Youwei Ma, Hyunwoo Park, Tae‐Lim Choi, Damien Guironnet, Francesco Stellacci   +5 more
wiley   +1 more source

Burnout, wellbeing and defensive medical practice in obstetricians and gynecologists in the UK before and after the COVID pandemic: A repeated cross‐sectional survey study

Acta Obstetricia et Gynecologica Scandinavica
Introduction There is evidence that burnout rates in doctors are high following the COVID pandemic, but with considerable variation across geographical location and specialty.
Nina Parker, Nora Falconieri, Harsha Shah, Christoph Lees, Dirk Timmerman, Ben Van Calster, Tom Bourne   +6 more
doaj   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

Advanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo, Nguyen Thi Nguyen, LiLi Guo, Ngoc Man Phan, Hyunsu Shin, Tae‐il Kim, Yu Seok Youn, Jaeyun Kim   +7 more
wiley   +1 more source

Machine learning and radiomics for segmentation and classification of adnexal masses on ultrasound

npj Precision Oncology
Ultrasound-based models exist to support the classification of adnexal masses but are subjective and rely upon ultrasound expertise. We aimed to develop an end-to-end machine learning (ML) model capable of automating the classification of adnexal masses.
Jennifer F. Barcroft, Kristofer Linton-Reid, Chiara Landolfo, Maya Al-Memar, Nina Parker, Chris Kyriacou, Maria Munaretto, Martina Fantauzzi, Nina Cooper, Joseph Yazbek, Nishat Bharwani, Sa Ra Lee, Ju Hee Kim, Dirk Timmerman, Joram Posma, Luca Savelli, Srdjan Saso, Eric O. Aboagye, Tom Bourne   +18 more
doaj   +1 more source