Results 91 to 100 of about 903,842 (287)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
The emerging role of the gut microbiota in vaccination responses
Gut MicrobesThe gut microbiota has emerged as a key modulator of host immune responses, and growing evidence suggests it plays a role in shaping vaccine-induced immunity.
V. Decker +6 more
doaj +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
The development of a mesh bioreactor for the anaerobic digestion of biodegradable municipal waste
, 2008 A laboratory scale prototype mesh bioreactor (MeBR) for the two-stage anaerobic digestion (AD) of biodegradable municipal waste (BMW) was successfully designed and tested.
Walker, Mark
core +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Food waste valorisation through anaerobic processes: thermal pretreatment or co-digestion?
, 2015 Anaerobic digestion of Food Wastes (FW) was investigated in batch mesophilic tests. Scope of this work was to evaluate the efficiency of thermal pretreatment on the solubilisation degree of FW, alone or mixed with typical Mediterranean agro-wastes as ...
Gallipoli, A. +3 more
core +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Comparison of static, in-vessel composting of MSW with thermophilic anaerobic digestion and combinations of the two processes [PDF]
, 2009 The biological stabilisation of the organic fraction of municipal solid waste (OFMSW) into a form stable enough for land application can be achieved via aerobic or anaerobic treatments. To investigate the rates of degradation (e.g.
Charles, W. +2 more
core
Thermophilic anaerobic digestion of food waste
, 2014 There is a requirement in the European Union to divert organic wastes from landfill because of the risk of methane emissions. One alternative is anaerobic digestion of organic wastes, such as food waste, to stabilise them whilst at the same time ...
Yirong, Chaowana
core +1 more source