Results 291 to 300 of about 1,334,985 (335)

Impact of fermentation on the processing and digestion characteristics of honeysuckle polyphenols by <i>Lactobacillus acidophilus</i>. [PDF]

Front Nutr
Dong X, Shi H, Zhang S, Deng X, Ge Y, Li Y.   +5 more
europepmc   +1 more source

Imiquimod‐Loaded Phospholipid‐Free Small Unilamellar Vesicles Activate the Tumor Immune Microenvironment to Treat Liver Cancer and Liver Metastases

Advanced Healthcare Materials, EarlyView.
Imiquimod‐loaded nanoparticles (PFSUV‐IMQ) are found to decrease liver metastasis and liver tumor burden when administered intravenously. Flow cytometry, RNA‐seq and various experiments show that the anti‐tumor response is immune‐mediated by activating dendritic cells resulting in increased CD8 T cell infiltration and activity.
Vanessa Chan, Hsin‐Mei Lee, Haruka Takata, Sheng‐Liang Cheng, Yu‐Ting Yen, Lisa Pfeifer, Luke Rushton, Po‐Han Chao, Feng Zhao, Chun Yat Ong, Nojoud Al‐Fayez, Tatsuhiro Ishida, Yunching Chen, Shyh‐Dar Li   +13 more
wiley   +1 more source

Engineering functionally-optimized aptamers against SARS-Cov-2 for blocking spike-ACE2 interaction and aptasensor detection. [PDF]

Mater Today Bio
Lai X, Zhao W, Jiang L, Li J, Munawer MF, Lai J, Juarez JAM, Ud Din M, Zhang X, Song Z, Wu T, Ge Y, Jiang H, Liu X, Wang X.   +14 more
europepmc   +1 more source

A Targeted Redox‐Active Dual‐Action Pt(IV)‐Mn(II) Prodrug Displays Enhanced In Vivo Anticancer Activity

Advanced Healthcare Materials, EarlyView.
A new oxaliplatin‐based Pt(IV) prodrug bearing a Mn(II) superoxide dismutase mimic is synthesized and studied, in vitro and in vivo, in the context of colorectal cancer. Encapsulation of this prodrug in an easy‐to‐implement PEGylated micelle formulation demonstrated the highest in vivo anticancer activity among all the tested conditions, supporting the
Alvaro Lopez‐Sanchez, Henri Chédotal, Ram Pravin Kumar Muthuramalingam, Marine Thomas, Jia Ning Nicolette Yau, Priya Ranjan Sahoo, Clotilde Policar, Frédéric Batteux, Kadda Medjoubi, Andrea Somogyi, Giulia Adriani, Carole Nicco, Romain Coriat, Giorgia Pastorin, Hélène C. Bertrand   +14 more
wiley   +1 more source

Systemic Characterization of the Pulp, Peels, and Seeds of the Yellow Puçá () and Impacts of Simulated In Vitro Gastrointestinal Digestion on the Chemical, Biological, and Antioxidant Properties of Polyphenols. [PDF]

ACS Omega
Soares CMDS, Morais RA, Oliveira MODS, da Silva RR, Sousa HMS, Queiroz F, Martins GAS.   +6 more
europepmc   +1 more source

DNA Barcoding‐Enabled Tracking of Lipid Nanoparticles: Drug‐Loading‐Dependent Biodistribution and Tumor Microenvironment Targeting

Advanced Healthcare Materials, EarlyView.
In this study, lipid nanoparticles are tracked in vivo using DNA barcodes to determine how varying drug loadings affect their delivery behaviors in mice. A cost‐effective strategy is developed for simultaneously monitoring the biodistribution of a library of lipid nanoparticles (LNPs).
Letao Xu, Rui Chen, Xing Wang, Dawei Liu, Yun liu, Chun‐Xia Zhao   +5 more
wiley   +1 more source

Chelator-mediated Fenton post-treatment enhances methane yield from lignocellulosic residues via microbial community modulation. [PDF]

Biotechnol Biofuels Bioprod
Martinez DV, Schambach JY, Davydovich O, Mascarenas MR, Butler SC, Kolker S, Salinas JE, Smallwood CR, Choudhary H, Quiroz-Arita C, Kent MS.   +10 more
europepmc   +1 more source

Porous Decellularized Nerve Grafts Facilitate Recellularization and Nerve Regeneration in a Rat Model of Critical Long‐Gap Peripheral Nerve Injury

Advanced Healthcare Materials, EarlyView.
A decellularized nerve graft (DNG) is modified to generate a porous DNG (PDNG). The PDNG is used to repair a 30‐mm peripheral nerve injury (PNI) defect, and is compared with isograft, serving as the standard, and DNG, a widely used alternative. The result shows that PDNG facilitated nerve regeneration in long‐gap PNI, evidenced by better‐aligned axonal
Olawale Alimi Alimi, Mitchell Kuss, Wen Xue, Bo Liu, Mena Asha Krishnan, Tianshu Pan, Zhi He, Han‐Jun Wang, Yuguo Lei, Kai Yang, Bin Duan   +10 more
wiley   +1 more source

Integrated transcriptome and metabolome analyses unraveled critical roles of small intestine during the weaning period of Vespertilio sinensis. [PDF]

BMC Genomics
Li Z, Guo W, Chu Y, Tan X, Wang H, Feng J, Liu T.   +6 more
europepmc   +1 more source

Comparative shotgun proteomics analysis of wheat gluten proteins digested by various peptidases. [PDF]

Curr Res Food Sci
Kaemper C, Mossburger J, Geyer M, Hartl L, Geisslitz S, Scherf KA.   +5 more
europepmc   +1 more source