Results 101 to 110 of about 2,631,756 (296)

Role of balloon dilation test in identifying suitable candidates for gastric peroral endoscopic myotomy

DEN Open
Background Predicting successful outcomes of gastric peroral endoscopic myotomy (G‐POEM) is essential for identifying patients who are most likely to benefit from the procedure.
Boldbaatar Gantuya, Haruhiro Inoue, Kazuki Yamamoto, Miyuki Iwasaki, Kei Ushikubo, Yohei Nishikawa, Hidenori Tanaka, Ippei Tanaka, Mayo Tanabe, Satoshi Abiko, Yuto Shimamura   +10 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Letter: A Role for Bacteria in Celiac Disease? in DIGESTIVE DISEASES AND SCIENCES, vol 61, issue 7, pp 2140-2140

, 2016
n ...
Sundqvist, Tommy,, Tjellstrom, Bo,, Norin, E,, Magnusson, K-E, Norin, Elisabeth,, Midtvedt, T, Magnusson, Karl-Eric,, Sundqvist, T, Stenhammar, L, Midtvedt, Tore,, Högberg, Lotta,, Stenhammar, Lars,, Tjellstrom, B, Hogberg, L   +13 more
core   +1 more source

Uncovering the Multitarget Therapeutic Mechanism of Tong-Xie-Yao-Fang on Irritable Bowel Syndrome

Journal of Food Quality
Background. This study investigated the pharmacological mechanisms of Tong-Xie-Yao-Fang (TXYF) against irritable bowel syndrome (IBS). Methods. The chemical profile of TXYF was identified through UHPLC-QTOF-MS.
Xiangxue Ma, Jinke Huang, Haomeng Wu, Xia Li, Fengyun Wang, Xudong Tang   +5 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Hyperglycemia-induced attenuation of rectal perception depends upon pattern of rectal balloon inflation. Digestive Diseases and Sciences

, 1997
This study investigated the effects of acute hyperglycemia on conscious rectal perception in response to two different rectal distension paradigms. Eleven healthy males were studied in random order on two separate days during euglycemia and hyperglycemia

core   +1 more source

Optimal number of the examined lymph nodes for different N stages in colorectal cancer

European Journal of Medical Research
The National Comprehensive Cancer Network (NCCN) recommends that at least 12 lymph nodes (LNs) should be harvested during radical surgery of colorectal cancer (CRC).
Ye Tian, Xinyu Qiao, Gaozan Zheng, Hanjun Dan, Xinyu Dou, Guangming Ren, Liaoran Niu, Pengfei Wang, Siyuan Wang, Fengsu Wu, Yumao Yang, Jianyong Zheng, Fan Feng   +12 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Desulfovibrio vulgaris interacts with novel gut epithelial immune receptor LRRC19 and exacerbates colitis

Microbiome
Background The overgrowth of Desulfovibrio, an inflammation promoting flagellated bacteria, has been found in ulcerative colitis (UC) patients. However, the molecular mechanism in promoting colitis remains unestablished.
Runxiang Xie, Yu Gu, Mengfan Li, Lingfeng Li, Yunwei Yang, Yue Sun, Bingqian Zhou, Tianyu Liu, Sinan Wang, Wentian Liu, Rongcun Yang, Xiaomin Su, Weilong Zhong, Bangmao Wang, Hailong Cao   +14 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source