Results 41 to 50 of about 120,914 (262)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Histological Structure and Enzyme Activities in the Digestive System of Octopus sinensis

Progress in Fishery Sciences, 2023
The East Asian common octopus (Octopus sinensis), is mainly distributed along the southeast coast of China. It has become an important aquaculture species in the coastal areas of the Fujian and Guangdong province due to its excellent culture features ...
Xuemei LI, Xingqiang WANG, Siqing CHEN, Fenghui LI, Qing CHANG, Baocheng DANG, Shouyong WEI, Li BIAN   +7 more
doaj   +1 more source

Digestion in Fish, Digestive Enzymes and Secretions

International Journal of Pure and Applied Sciences, 2017
Yeni besleme rejimleri gelistirmede ve optimal yetistirme sartlarini saglayabilme calismalarinda sindirim enzim aktivitelerinin tespiti onem arz etmektedir. Ayrica cogu enzimler, canlilik olaylarini duzenledikleri icin, aktivitelerindeki artis ya da azalislar baliklarin normal fonksiyonlarinin bozulmasina ve baliklarda hastaliklara neden olmaktadir. Bu
Mücahit Yüngül, Yaşar Özdemir
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Ontogenetic digestive physiology and expression of nutrient transporters in Anguilla japonica larvae

Aquaculture Reports, 2022
Freshwater eel (Anguilla japonica) is the main aquaculture fish species in Korea, but artificial mass seed production has not been succeeded yet; eel aquaculture is therefore dependent on the seed of wild catches.
Min Gyu Shin, Yongwoon Ryu, Youn Hee Choi, Shin-Kwon Kim   +3 more
doaj   +1 more source

Studies on Digestive Enzymes of Fishes-II

NIPPON SUISAN GAKKAISHI, 1971
The activities of various kinds of carbohydrases in the digestive organs of several fishes were determined with TAUBER-KLEINER's method modified by the authors. The results obtained were as follows. Adult carp showed marked maltase, amylase, and weak sucrase, lactase, melibiase, cellobiase and methyl-α-D-glucosidase activities in the intestine.
Shin-ichiro KAWAI, Shizunori IKEDA
openaire   +5 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Proteinase-Activated Receptors of Digestive Systems

Медицинский вестник Юга России, 2012
The enzymes exosecreted by digestive glands, especially proteinases have not only digestive but signal role. The role is realized by means of regulatory peptide formation, stimulation and inhibition of their release, stimulation of special proteinase ...
G. F. Korotko
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source