Results 121 to 130 of about 22,831,370 (389)

Health Effects Associated With Electronic Cigarette Use: Automated Mining of Online Forums. [PDF]

, 2020
BACKGROUND:Our previous infodemiological study was performed by manually mining health-effect data associated with electronic cigarettes (ECs) from online forums.
Hristidis, Vagelis, Hua, My, Sadah, Shouq, Talbot, Prue   +3 more
core  

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Psychological impact of risk-reducing surgery for gynecologic cancer among women with Lynch syndrome

Gynecologic Oncology Reports
Objective: Prophylactic total hysterectomy and bilateral salpingo-oophorectomy are risk-reducing surgeries (RRS) that can be offered to women with Lynch syndrome (LS) as they reduce the incidence of ovarian and endometrial cancer.
Helen Huband, Kaitlin M McGarragle, Crystal J Hare, Melyssa Aronson, Thomas Ward, Kara Semotiuk, Sarah E Ferguson, Zane Cohen, Tae L Hart   +8 more
doaj   +1 more source

アコヤガイ由来抗菌物質の性状に関する研究 [PDF]

, 2017
東京海洋大学博士学位論文 平成28年度(2016) 応用生命科学 課程博士 甲第427号指導教員: 石崎松一郎全文公表年月日: 2018-07 ...
林 海生
core   +1 more source

Medicinal plants used to treat acute digestive system problems in the region of Fez-Meknes in Morocco: An ethnopharmacological survey

, 2020
Background: In Morocco, acute digestive system problems appear to be a famous daily ill which the most population deal with using medicinal plants. This work aims to inventory the plants used to deal with acute digestive system problems in the region of ...
I. Es-safi, Hamza Mechchate, Amal Amaghnouje, F. Jawhari, A. Bari, P. Cerruti, Maurizio Avella, Andriy Grafov, D. Bousta   +8 more
semanticscholar   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Development of esophagogastroduodenoscopy in China: results from the national census in 2013 and 2020

Frontiers in Oncology
BackgroundGiven the significant burden of upper digestive diseases, there has been a substantial increase in the utilization of esophagogastroduodenoscopy (EGD) in China from 2012 to 2019.
Siwei Zhou, Siwei Zhou, Zheran Chen, Zheran Chen, Yunfei Jiao, Yunfei Jiao, Zhiyuan Cheng, Zhiyuan Cheng, Zhiyuan Cheng, Ye Gao, Ye Gao, Tianjiao Wang, Tianjiao Wang, Lei Xin, Lei Xin, Rong Wan, Luowei Wang, Luowei Wang   +17 more
doaj   +1 more source

Cloning of the Neurodegeneration Gene \u3cem\u3eDrop-Dead\u3c/em\u3e and Characterization of Additional Phenotypes of its Mutation [PDF]

, 2008
Mutations in the Drosophila gene drop-dead (drd) result in early adult lethality and neurodegeneration, but the molecular identity of the drd gene and its mechanism of action are not known.
Blumenthal, Edward M.
core   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source