Mechanisms of Anti-PD Therapy Resistance in Digestive System Neoplasms. [PDF]
Wu Y+5 more
europepmc +1 more source
Protease‐degradable hydrogels mimic dynamic cell‐matrix interactions, but controlling hydrogel degradation is a challenge. We screen libraries of peptides to identify sequences that are primarily degraded by membrane‐localized proteases. Crosslinking hydrogels with these peptides enables cell to spread and migrate while reducing matrix degradation ...
Yingjie Wu+3 more
wiley +1 more source
[Interest in gnotoxenic systems for the study of host-microbial flora of the digestive tract].
R Ducluzeau, P Raibaud
openalex
This work presents a “tooth‐on‐chip” device that mimics dental pulp tissue. By co‐culturing key cell types, it recreates vascular networks, stem cell niches, the odontoblast/dentine interface, and trigeminal innervation. This innovative platform provides a unique model of dental pulp structure and physiology, with significant potential for accelerating
Alessandro Cordiale+6 more
wiley +1 more source
Drug repositioning for pan-cancers of the digestive system: Identification of amonafide and BX795 as potential therapeutics via integrative Omics analysis. [PDF]
Liu W, Gao J, Ren S, Nashun B, Gao F.
europepmc +1 more source
Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases
This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun+9 more
wiley +1 more source
Scutellaria baicalensis and its flavonoids in the treatment of digestive system tumors. [PDF]
Zhao K, Zhang J, Zhou L, Sun Z.
europepmc +1 more source
A stable composite pH sensor is developed by coating graphene oxide (GO) nanosheets with covalent organic frameworks (COFs) to improve stability and sensitivity in acidic environments. The GO/COFs sensor demonstrates high selectivity, linearity, and biocompatibility, offering a promising strategy for continuous pH monitoring in gastro‐esophageal reflux
Ahmed H. M. Salem+6 more
wiley +1 more source
Metformin and the risk of malignant tumors of digestive system: a mendelian randomization study. [PDF]
Liu P, Xiao J, Xiao J, Zhou J.
europepmc +1 more source
Histological and molecular characterization of the digestive system of early weaned juveniles of Arapaima sp. reared in a recirculating aquaculture system. [PDF]
Darias MJ+7 more
europepmc +1 more source