Results 61 to 70 of about 1,487,193 (321)
NLRP3 inflammasome in digestive diseases: From mechanism to therapy
Frontiers in Immunology, 2022 Digestive system diseases remain a formidable challenge to human health. NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome is the most characteristic multimeric protein complex and is involved in a wide range of digestive diseases ...
Rui Qiang +3 more
semanticscholar +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Diseases of the digestive system
Kazan medical journal, 1934 In the preface to his book, Prof. R.A. Luria writes: "Diseases of the digestive organs are undoubtedly the most frequent diseases with which the therapist has to deal. It is impossible not to agree with this, as well as with the idea that this area of internal medicine is the least familiar to a wide range of physicians.
openaire +2 more sources
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
Frontiers in Integrative Neuroscience, 2019 Background and objective: Developing therapy for non-motor symptoms of Parkinson’s disease (PD) is important for improving patients’ quality of life.
Artem Minalyan +6 more
doaj +1 more source
A systematic review on application of deep learning in digestive system image processing
The Visual Computer, 2021 With the advent of the big data era, the application of artificial intelligence represented by deep learning in medicine has become a hot topic . In gastroenterology, deep learning has accomplished remarkable accomplishments in endoscopy, imageology, and
Huangming Zhuang +2 more
semanticscholar +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
The Use of Medicinal Plants in Digestive System Related Disorders- A Systematic Review
Journal of Ayurvedic and Herbal Medicine, 2021 The most prevalent forms of ailments affecting a huge number of individuals throughout the world are digestive system problems. According to the World Health Organization (WHO), over 100 million people died globally as a result of digestive system ...
H. S. Cheema, Mitra Pal Singh
semanticscholar +1 more source
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source