Results 81 to 90 of about 334,417 (282)

The parasympathetic and sensory innervation of the proximal and distal colon in male mice

Frontiers in Neuroanatomy
IntroductionThe distributions of extrinsic neurons innervating the colon show differences in experimental animals from humans, including the vagal and spinal parasympathetic innervation to the distal colon.
Lixin Wang, Lixin Wang, Yvette Taché, Yvette Taché   +3 more
doaj   +1 more source

Dataset for evaluation of threescoring systems for forecasting the clinical outcomes of patients with upper gastrointestinal bleeding (UGIB) – Ahvaz, Iran

Data in Brief, 2018
Upper gastrointestinal bleeding (UGIB) which occurs proximal to the Treitz ligament is one of the most common cases is emergency medical conditions. The aim of this data article is to evaluation of Rockall and Blatchford scoring systems for predicting ...
Seyed Saeidseyedian, Ali Akbar Shayesteh, Fereshteh Beyranvandi   +2 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Digestive System Diseases, Genetic Risk, and Incident Dementia : A Prospective Cohort Study

Introduction: Although digestive system disease affects gut microbiota and their metabolites associated with dementia risk, the association between digestive system diseases and incident dementia has not yet been established.Methods: This cohort analysis
Kivipelto, Miia,, Ludvigsson, Jonas F, Larsson, Susanna C, Zhao, Jianhui,, Zhao, Jianhui, Kivipelto, Miia, Chen, Jie,, Ludvigsson, Jonas F.,, Chen, Jie, Dan, Lintao,, Yuan, Shuai,, Wu, Jing, Zhang, Yao,, Li, Xue, Dan, Lintao, Yuan, Shuai, Zhang, Yao, Li, Xue,, Larsson, Susanna C.,, Wu, Jing,   +19 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Dynamics of prevalence of diseases of the digestive system among the population of different age groups in conditions of social stress [PDF]

, 2018
Objective: to analyze the prevalence of digestive diseases during social stress among the population of different age groups (young, mature, elderly / old). Material and Methods.
Lipatova TE, Denisova TP, Tyultyaeva LA, Kovalev EP.   +3 more
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Oral administration of Sophora Flavescens-derived exosomes-like nanovesicles carrying CX5461 ameliorates DSS-induced colitis in mice

Journal of Nanobiotechnology
Ulcerative colitis (UC) belongs to chronic inflammatory disease with a relapsing characterization. Conventional oral drugs of UC are restricted in clinical by premature degradation in the gastrointestinal tract, modest efficacy, and adverse effects ...
Manqi Zhang, Xichao Xu, Liqian Su, Yuqing Zeng, Jingxiong Lin, Wenwen Li, Yigui Zou, Sicong Li, Boxian Lin, Ziyuan Li, Hu Chen, Yuheng Huang, Quanle Xu, Hongbo Chen, Fang Cheng, Dongling Dai   +15 more
doaj   +1 more source

Role of yoga in the management of digestive system disorders

Environment Conservation Journal, 2017
A healthy digestive system is the key to total health. Digestive system diseases contribute a big proportion of all pathologies. Yoga is being recognised worldwide as the solution to these problems.
Manorma Singh
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source