Results 101 to 110 of about 334,417 (282)

The Regulatory Functions of Circular RNAs in Digestive System Cancers

, 2020
Circular ribonucleic acids (circRNAs), which are a type of covalently closed circular RNA, are receiving increasing attention. An increasing amount of evidence suggests that circRNAs are involved in the biogenesis and development of multiple diseases ...
Bo Zeng, Mingyao Yang, Ya Yuan, Qingyong Ni, Deying Yang, Diyan Li, Xiao Yuan, Zhi He   +7 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Peculiarities of the digestive system organs’ triad diseases сlinic and treatment

, 2019
Проведено дослідження клініки тріади захворювань органів системи травлення з обґрунтуванням запропонованого нами методу лікування у 40 хворих при поєднанні дуоденальної виразки, холециститу і панкреатиту.
Dudchenko, M. O., Сорокіна, Світлана Іванівна, Kryvoruchko, I. G., Третяк, Наталья Григорьевна, Tretiak, N. G., Дудченко, Максим Александрович, Криворучко, Іван Григорович, Третяк, Наталія Григорівна, Сорокина, Светлана Ивановна, Дудченко, Максим Андрійович, Дудченко, Максим Олександрович, Dudchenko, M. A., Дудченко, Максим Андреевич, Sorokina, S. I., Криворучко, Иван Григорьевич   +14 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

METABOLIC SYNDROME AND METABOLISM-ASSOCIATED DISEASES OF THE DIGESTIVE SYSTEM

, 2017
The article described a typical clinical situation that is frequently observed in the pediatric practice and probably will be more prevalent as the incidence of the metabolic syndrome continues to grow.
N. I. Ursova
core   +1 more source

Surgical-site infection risk in oncologic digestive surgery [PDF]

, 2011
Surgical-site infection (SSI) is the most prevalent type of hospital infection in surgical patients and is associated with an increase in hospital stay, costs and morbidity/lethality.
PASSOS, Afonso Dinis Costa, CARVALHO, André Lopes, FOSCHINI, Milene Mitsuyuki, Costa Passos, Afonso Dinis, PERES, Stela Verzinhasse, e Castro, Paulo de Tarso Oliveira, CASTRO, Paulo de Tarso Oliveira e   +6 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

Role of Endoscopic Ultrasound in Pancreatic Cancer Diagnosis and Management

Diagnostics
The emergence of endoscopic ultrasound (EUS) has significantly impacted the diagnosis and management of pancreatic cancer and its associated sequelae. While the definitive role of EUS for pancreatic cancer remains incompletely characterized by currently ...
Hayley K. Rogers, Shawn L. Shah
doaj   +1 more source