Results 41 to 50 of about 107,528 (272)

Diagnosis and therapy of neuroendocrine neoplasms of the gastrointestinal tract

open access: yesFamily Medicine & Primary Care Review, 2016
A neuroendocrine neoplasm (NEN) is a tumor that originates in neuroendocrine cells capable of producing peptides or amines. Neuroendocrine neoplasms of the digestive system are also referred to as gastroenteropancreatic neuroendocrine neoplasms (GEP NEN)
Andrzej Deptała   +1 more
doaj   +1 more source

Morphological classification of digestive neuroendocrine neoplasms: the current concepts and controversies

open access: yesУспехи молекулярной онкологии, 2016
Neuroendocrine tumors comprise the heterogeneous group of malignant epithelial neoplasms, the diagnosis of which is based on their histopathologic features and immunohistochemical profile.
V. V. Delektorskaya
doaj   +1 more source

Gastric Hyperplastic Polyps: A Benign Entity? Analysis of Recurrence and Neoplastic Transformation in a Cohort Study

open access: yesGE: Portuguese Journal of Gastroenterology, 2021
Introduction: Hyperplastic polyps represent 30–93% of all gastric epithelial polyps. They are generally detected as innocuous incidental findings; however, they have a risk of neoplastic transformation and recurrence.
Mafalda João   +7 more
doaj   +1 more source

ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms of the Digestive System

open access: yesЭндокринная хирургия, 2012
Панкреатические нейроэндокринные опухоли (П-НЭО) представлены как функционирующими опухолями, так и новообразованиями без определенной функциональной активности [1–4]. Нефункционирующие П-НЭО часто секретируют панкреатический полипептид (ПП), хромогранин
D G Beltsevich
doaj   +1 more source

Mixed adenoneuroendocrine carcinomas of stomach and ampulla of vater after curative-intent resection: a single center cases series

open access: yesBMC Gastroenterology, 2021
Background Mixed adenoneuroendocrine carcinoma is a rare clinical manifestation, especially in the gastric and ampullary. The purpose of this study was to investigate the clinicopathological features and prognosis of mixed adenoneuroendocrine carcinoma ...
Sishu Yang   +4 more
doaj   +1 more source

Endoscopic Submucosal Dissection of an Inverted Early Gastric Cancer-Forming False Gastric Diverticulum [PDF]

open access: yesClinical Endoscopy, 2016
Endoscopic submucosal dissection (ESD) is a standard treatment for early gastric cancer (EGC) that does not have any risk of lymph node or distant metastases. Here, we report a case of EGC resembling a diverticulum.
Yong-il Lee, Sang-kil Lee
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The potential of kaempferol in digestive system tumors: recent advances and mechanistic insights

open access: yesDiscover Oncology
Digestive system neoplasms are a heterogeneous group of cancers characterized by diverse symptoms, complex diagnosis, and treatment. Prognosis is poor and influenced by multiple factors, making early detection and comprehensive treatment crucial for ...
Xunxing Hao   +5 more
doaj   +1 more source

Introduction to neuroendocrine neoplasms of the digestive system: definition and classification

open access: yesPathologica, 2021
Neoplasms characterized by the expression of markers of neuroendocrine differentiation in neoplastic cells are defined neuroendocrine. This broad definition comprises tumors found at different sites of the body with similar morphology but different behavior and genetic background.
Inzani, Frediano, Rindi, Guido
openaire   +4 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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