Results 141 to 150 of about 134,814 (305)
Do Patients Bypass Rural Hospitals? Determinants of Inpatient Hospital Choice in Rural California [PDF]
Rural hospitals play a crucial role in providing healthcare to rural Americans, a vulnerable and underserved population; however, rural hospitals have faced threats to their financial viability and many have closed as a result.
José J Escarce, Kanika Kapur
core
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth+2 more
wiley +1 more source
Methodology for estimation of total body composition in laboratory mammals [PDF]
A standardized dissection and chemical analysis procedure was developed for individual animals of several species in the size range mouse to monkey (15 g to 15 kg). The standardized procedure permits rigorous comparisons to be made both interspecifically
Pace, N., Rahlmann, D. F., Smith, A. H.
core +1 more source
This study presents an injectable hydrogel that responds to Pseudomonas aeruginosa infection by releasing a dual‐phage cocktail on demand. The system degrades selectively in infected wounds, enhances phage localization and stability, and shows potent antibiofilm activity and biocompatibility in an ex vivo human skin model—offering a promising strategy ...
Siyuan Tao+9 more
wiley +1 more source
Highly Selective Toward HER or CO2RR by Regulating Cu Single and Dual Atoms on g‐C3N4
This systematic study provides insights into the design of electrocatalysts for hydrogen evolution reaction (HER) and carbon dioxide reduction (CO2RR). It serves as a useful guide for tuning catalyst architecture toward efficient multifunctional performance by varying synthetic parameters, demonstrating the impact of copper (Cu) species ranging from ...
Wan‐Ting Chen+9 more
wiley +1 more source
Bioinspired Design of a Wet‐Adhesive Cornea Glue Based on Recombinant Human Protein Networks
Natures protein‐based high performance materials e.g. elastin, silk and muscle proteins have been mimicked by a new protein‐hybrid material based on redesigned human partial sequences only, showing high wet‐adhesiveness and elasticity for biomedical applications.
Anna Resch+17 more
wiley +1 more source
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche+16 more
wiley +1 more source
Thermoresponsive BrushGel Microcarriers for Efficient Cell Expansion and Enzyme‐Reduced Harvesting
Askari et al, report on temperature‐responsive microcarriers to minimize enzyme use and cost in dynamic cultures. Abstract Scaling up cell therapy requires efficient expansion of high‐quality cells. Microcarrier(MC)‐based systems offer high surface‐to‐volume ratios and reduce culture media usage.
Esfandyar Askari+9 more
wiley +1 more source
Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq+4 more
wiley +1 more source
Rapid Deep Vat Printing Using Photoclickable Collagen‐Based Bioresins
Collagen‐based resin formulations based on thiol‐ene photoclick chemistry are demonstrated. These resins enable easy handleability under neutral conditions and further allow facile fabrication of multicellular tissue constructs via tomographic or FLight printing.
Michael Winkelbauer+8 more
wiley +1 more source