Results 121 to 130 of about 1,330,094 (399)

Traditional serrated adenomas of the upper digestive tract

Journal of Clinical Pathology, 2015
For many years, it was generally accepted that the vast majority of the colorectal carcinomas (CRCs) evolved from conventional adenomas, via the adenoma–carcinoma sequence.
C. Rubio
semanticscholar   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Thoracoscopic esophagectomy with gastric pull-up in megaesophagus secondary to terminal achalasia

Revista Médica del Hospital General de México
In terminal achalasia, the presence of a megaesophagus with loss of axis in its distal third or persistence of symptoms despite multiple previous treatments, the esophagectomy by thoracoscopy with reconstruction by laparoscopic gastric ascent and ...
Rafael Rivera-Avalos, Verónica Rojas-Hernández, César G. Rojas-Benítez, Ernesto Castellanos-Flores, Francisco R. Higuera-Hidalgo, Agustín Etchegaray-Dondé   +5 more
doaj  

The Critical Role of Chemokine (C–C Motif) Receptor 2-Positive Monocytes in Autoimmune Cholangitis

Frontiers in Immunology, 2018
The therapy of primary biliary cholangitis (PBC) has lagged behind other autoimmune diseases despite significant improvements in our understanding of both immunological and molecular events that lead to loss of tolerance to the E2 component of pyruvate ...
Debby Reuveni, Debby Reuveni, Yael Gore, Yael Gore, Patrick S. C. Leung, Yael Lichter, Yael Lichter, Itay Moshkovits, Itay Moshkovits, Ayelet Kaminitz, Ayelet Kaminitz, Eli Brazowski, Eli Brazowski, Eric Lefebvre, Pamela Vig, Chen Varol, Chen Varol, Zamir Halpern, Zamir Halpern, Oren Shibolet, Oren Shibolet, Merrill Eric Gershwin, Ehud Zigmond, Ehud Zigmond   +23 more
doaj   +1 more source

Management of a Case of Colovesical Fistula with Fecaluria as First Sign [PDF]

, 2015
Introduction. Fecaluria and pneumaturia are the patognomonic signs of an abnormal communication between the bladder and the intestinal tract. Therefore, when a history of digestive signs, symptoms or digestive diseases is missing, this borderline ...
Andresanu, A., Baston, C., Brasoveanu, V., Crasneanu, M., Dick, A., Domnisor, L., Gingu, C., Ianiotescu, I., Martiniuc, A., Sinescu, I.   +9 more
core   +2 more sources

A Proteomic Analysis of the Body Wall, Digestive Tract, and Reproductive Tract of Brugia malayi

PLoS Neglected Tropical Diseases, 2015
Filarial worms are parasitic nematodes that cause devastating diseases such as lymphatic filariasis (LF) and onchocerciasis. Filariae are nematodes with complex anatomy including fully developed digestive tracts and reproductive organs.
C. P. Morris, C. P. Morris, S. Bennuru, Laura E Kropp, Jesse A. Zweben, Z. Meng, Rebekah T. Taylor, King-man Chan, T. Veenstra, T. Nutman, E. Mitre   +10 more
semanticscholar   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source

Neural Circuits between Nodose Ganglion and Pulmonary Neuroendocrine Cells Regulate Lung Inflammatory Responses

Advanced Science, EarlyView.
TRPA1+αCGRP+ sensory neurons in the nodose ganglion detect external insults such as lipopolysaccharide (LPS) and interact directly with pulmonary neuroendocrine cells (PNECs), promoting their activation and proliferation. This neural‐epithelial interaction amplifies lung inflammation.
Jie Chen, Shitao Xie, Zhekai Lin, Caiqi Zhao, Rujia Tao, Yingying Ma, Xiaoyan Chen, Renlan Wu, Qingjian Han, Pengfei Sui, Sheng Wang, Hongbin Ji, Hai Song, Xiaoming Zhang, Yangang Sun, Yuanlin Song, Xiao Su   +16 more
wiley   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Role of mitomycin in upper digestive tract stricture [PDF]

, 2006
M. Boyd Gillespie, Terry A. Day, Anand K. Sharma, Martin B. Brodsky, Bonnie Martin‐Harris   +4 more
openalex   +1 more source