Results 131 to 140 of about 386,338 (306)

Oral Bioinspired Peroxisome‐Engineered Probiotics for Modulating Gut Microbiota Homeostasis and Alleviating Cardiac Chemotherapy Toxicity

open access: yesAdvanced Science, EarlyView.
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang   +10 more
wiley   +1 more source

Preliminary exploratory research on the application value of oral and intestinal meta-genomics in predicting subjects' occupations–A case study of the distinction between students and migrant workers

open access: yesFrontiers in Microbiology
BackgroundIn the field of forensic science, accurately determining occupation of an individual can greatly assist in resolving cases such as criminal investigations or disaster victim identifications. However, estimating occupation can be challenging due
Shujie Dou   +10 more
doaj   +1 more source

Predisposing factors in enterotoxemias of camels (Camelus dromedarius) caused by Clostridium perfringens type A [PDF]

open access: yes, 1991
Clostridium perfringens type A a été isolé à partir de différents organes et d'intestins prélevés sur des dromadaires d'élevage et de course, morts des suites d'entérotoxémies aiguës et subaiguës dans deux foyers distincts.
Ali, M.   +3 more
core  

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

open access: yesAdvanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao   +12 more
wiley   +1 more source

Intestinal intussusception as a metastatic presentation of Acral Melanoma – Case report

open access: yesCurrent Problems in Cancer: Case Reports
Introduction: Acral melanoma is a clinical subtype of melanoma that occurs on surfaces that do not develop hair, frequently metastasizes, and presents significant recurrence.
Monserrat Martínez Zamorano   +4 more
doaj   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

open access: yesAdvanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu   +16 more
wiley   +1 more source

Evaluation of the gastric conduit perfusion using indocyanine green in thoracoscopic esophagectomy for esophageal cancer

open access: yesSAGE Open Medicine
Objective: Indocyanine green has been used in the assessment of the gastric conduit perfusion in thoracoscopic esophagectomy to prevent malperfusion-associated anastomotic leak. This study aims to evaluate the initial results of investigating the gastric
Tiep Nguyen Van   +7 more
doaj   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

open access: yesAdvanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu   +18 more
wiley   +1 more source

Comparison of ustekinumab, infliximab and combination therapy in moderately to severely active ulcerative colitis – a study protocol of a randomized, multicenter, head-to-head COMBO-UC trial

open access: yesFrontiers in Medicine
BackgroundUlcerative colitis (UC) is a chronic inflammatory bowel disease with a complex etiology that affects the large intestine. Characterized by chronic, bloody diarrhea, UC can lead to severe complications, including an increased risk of colorectal ...
Renata Talar-Wojnarowska   +8 more
doaj   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

open access: yesAdvanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang   +12 more
wiley   +1 more source

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