Results 41 to 50 of about 106,131 (262)
Twice‐input variable‐resolution single‐side switching scheme without reset energy for SAR ADC
A twice‐input variable‐resolution single‐side switching scheme without reset energy is proposed for successive approximation register (SAR) analogue‐to‐digital converters (ADCs).
Bin Tang +6 more
doaj +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Design of optimal and asymptotically optimal quantisation subject to the mean squared error (MSE) criterion is a complex issue, even in the case of uniform scalar quantisation (USQ).
Aleksandra Jovanović +2 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes
An outstanding question is how receptor tyrosine kinases (RTKs) determine different cell-fate decisions despite sharing the same signalling cascades. Here, we uncovered an unexpected mechanism of RTK trafficking in this process.
Roberto Villaseñor +4 more
doaj +1 more source
Processing Methods for Digital Image Data Based on the Geographic Information System
Digital image data processing is mainly to input digital image data into a computer to complete the conversion of a continuous spatially distributed image model into a discrete digital model so that the computer can identify, process, and store the ...
Xi Wang +3 more
doaj +1 more source
Testing high resolution SD ADC’s by using the noise transfer function [PDF]
A new solution to improve the testability of high resolution SD Analogue to Digital Converters (SD ADC’s) using the quantizer input as test node is described.
Richardson, Andrew, De-Venuto, Daniela
core
Whisper-to-speech conversion using restricted Boltzmann machine arrays [PDF]
Whispers are a natural vocal communication mechanism, in which vocal cords do not vibrate normally. Lack of glottal-induced pitch leads to low energy, and an inherent noise-like spectral distribution reduces intelligibility.
Li, Jing-jie +3 more
core +1 more source

