Results 81 to 90 of about 702,324 (296)

Davis Digital Repository Grant [PDF]

, 2005
The HELIN (Higher Education Library Information Network) Consortium, consisting of academic and health sciences libraries in Rhode Island and Massachusetts, has developed a plan to create a digital repository to archive, preserve and make accessible ...
Aspri, Bob, Sanders, Martha Rice
core   +1 more source

My digital photos: where and when? [PDF]

, 2005
In recent years digital cameras have seen an enormous rise in popularity, leading to a huge increase in the quantity of digital photos being taken. This brings with it the challenge of organising these large collections.
Gurrin, Cathal, Jones, Gareth J.F., Lee, Hyowon, Murphy, Noel, O'Hare, Neil, Smeaton, Alan F.   +5 more
core   +1 more source

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Planning and managing the cost of compromise for AV retention and access [PDF]

, 2012
Long-term retention and access to audiovisual (AV) assets as part of a preservation strategy inevitably involve some form of compromise in order to achieve acceptable levels of cost, throughput, quality, and many other parameters.
addis, barroso, cunningham, jiang, miller, moore, surridge   +6 more
core   +1 more source

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

Advanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian, Sreenidhi Mohanvelu, Sheeja Aravindan, Afsana Parveen Jahir Hussain, Sivasubramani Narayanan, Sabir Salim, Loganayaki Periyasamy, Natarajan Aravindan   +7 more
wiley   +1 more source

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

Advanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen, Bo Pang, Yun Liu, Jiangwei Wang, Lanhui Zheng, Yuzhou Chang, Yingxuan Sun, Haoyuan Sun, Huiyuan Chen, Jiawei Cai, Zanyi Wu, Qing Chang, Yongzhi Wang, Dezhi Kang, Tao Jiang, Ruichao Chai   +15 more
wiley   +1 more source

Fortunoff Video Archive: New Initiatives for a New Digital Archive

Umanistica Digitale, 2019
The Fortunoff Archive recently completed a number of important milestones including the digitization of its entire collection, the development of a digital access system, migration of legacy metadata, and the launch of a partner site program that ...
Kevin Glick, Stephen Naron
doaj   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

POLA PENGELOLAAN ARSIP DIGITAL DALAM MENDUKUNG KEMAMPUAN ORGANISASI DI DPUPRPKP KOTA MALANG

BIBLIOTIKA: Jurnal Kajian Perpustakaan dan Informasi
The development of advanced information technology can make it easier for every agency to manage important documents. Archives are one of the important documents that must be managed by archivists, which will later be used as accountability materials ...
Laily Khoiri Syafiya, Sokhibul Ansor, Adi Prasetyawan   +2 more
doaj   +1 more source