Results 81 to 90 of about 3,919,107 (321)

Legal Deposit Web Archives and the Digital Humanities: a Universe of Lost Opportunity? [PDF]

open access: yes, 2018
Legal deposit libraries have archived the web for over a decade. Several nations, supported by legal deposit regu-lations, have introduced comprehensive national domain web crawling, an essential part of the national library re-mit to collect, preserve ...
Berube, Linda   +2 more
core   +3 more sources

A Perspective on Interactive Theorem Provers in Physics

open access: yesAdvanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

The Gut Commensal Butyricimonas Virosa Modulates Gut Microbiota‐Dependent Thiamine Metabolism and Attenuates Mouse Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
This study reveals that dietary stachyose enriches Butyricimonas virosa, effectively attenuating metabolic dysfunction‐associated steatotic liver disease (MASLD). Mechanistically, B. virosa enhances gut thiamine monophosphate synthesis, which elevates hepatic thiamine pyrophosphate levels.
Ningning He   +17 more
wiley   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

open access: yesAdvanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan   +20 more
wiley   +1 more source

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

open access: yesAdvanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian   +7 more
wiley   +1 more source

Fortunoff Video Archive: New Initiatives for a New Digital Archive

open access: yesUmanistica Digitale, 2019
The Fortunoff Archive recently completed a number of important milestones including the digitization of its entire collection, the development of a digital access system, migration of legacy metadata, and the launch of a partner site program that ...
Kevin Glick, Stephen Naron
doaj   +1 more source

The European Landscape of Qualitative Social Research Archives: Methodological and Practical Issues [PDF]

open access: yes, 2011
In this article I set about describing current practices in archiving and reusing qualitative data. I discuss where can you find archived sources of qualitative data, and discuss some of the debates surrounding methodological, ethical and theoretical ...
Corti, Louise
core   +3 more sources

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

open access: yesAdvanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen   +15 more
wiley   +1 more source

POLA PENGELOLAAN ARSIP DIGITAL DALAM MENDUKUNG KEMAMPUAN ORGANISASI DI DPUPRPKP KOTA MALANG

open access: yesBIBLIOTIKA: Jurnal Kajian Perpustakaan dan Informasi
The development of advanced information technology can make it easier for every agency to manage important documents. Archives are one of the important documents that must be managed by archivists, which will later be used as accountability materials ...
Laily Khoiri Syafiya   +2 more
doaj   +1 more source

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