Results 151 to 160 of about 35,571,787 (246)

Data Notes: A New Article Type for Preserving and Sharing Biodiversity Data. [PDF]

Ecol Evol
Soares BE, Jenkins GB.
europepmc   +1 more source

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Dataset on psychological determinants of impulsive buying in Vietnamese social commerce. [PDF]

Data Brief
Mai LVT, Nguyen HN.
europepmc   +1 more source

First‐in‐human, phase I, randomized, safety, pharmacokinetic, food‐effect and pharmacodynamic study of a tyrosine kinase 2/Janus kinase 1 inhibitor, SDC‐1801

British Journal of Clinical Pharmacology, EarlyView.
Aim The purpose of this study is to evaluate safety, tolerability, pharmacokinetics (PK), food‐effect (FE) and pharmacodynamics (PD) of an oral tyrosine kinase‐2 (TYK2)/Janus kinase‐1 (JAK1) inhibitor, SDC‐1801, in healthy adult participants. Methods This first‐in‐human study randomized 95 male and female participants.
Chris Brearley, Sam Francis, John Reader, Judi Proctor   +3 more
wiley   +1 more source

Mapping Echocardiographic Practice in Emilia-Romagna: A Regional Healthcare Census. [PDF]

J Clin Med
Barbieri A, Mantovani F, Bursi F, Malaguti M, Fortuni F, Moderato L, Bartolacelli Y, Binno S, Malagoli A, Pavasini R, Pedone C, Suma S, Squeri A, Albini A, Vermi AC, Di Giannuario G, Laurito M, Li Calzi M, Navazio A, Moreo A, Di Salvo G, Carerj S.   +21 more
europepmc   +1 more source

Sustained pharmacodynamic effects of S‐ketamine on cortical excitability and resting‐state brain activity: A randomized, placebo‐controlled trial

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to investigate a set of pharmacodynamic biomarkers reflecting acute, delayed and sustained central nervous system effects of S‐ketamine, used as a tool compound for rapid‐acting antidepressant activity, with the goal of informing biomarker strategies for delayed antidepressant effects.
Catherine M. K. E. de Cuba, Annika A. de Goede, Joost. C. van Mechelen, Laura G. J. M. Borghans, Liam van der Aa, Erik Olofsen, Maria J. Juachon, Robert J. Doll, Amy Gillespie, Catherine J. Harmer, Gabriël E. Jacobs, Jules A. A. C. Heuberger   +11 more
wiley   +1 more source

Lithuania's National Digital Health System Architecture, Evolution, and Lessons From a Centralized Approach Using Longitudinal Document Analysis: Descriptive National Case Study. [PDF]

JMIR Form Res
Dapkutė A, Niakšu O, Juodakis J, Jankauskienė D, Trinkūnas J, Laurinavičius A, Jovaiša T, Ringaitienė D, Atraškevičienė M, Masiliūnas R.   +9 more
europepmc   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Mobile health interventions to improve adherence to oral anticoagulant treatment: A systematic review and critical analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Non‐adherence to oral anticoagulants (OACs) is associated with significant morbidity and mortality. Mobile health (mHealth) interventions have been used to improve medication adherence across the three phases of initiation, implementation and persistence.
Non Davies, Elin Haf Davies, Dyfrig A. Hughes   +2 more
wiley   +1 more source

Guidelines for the adoption of digital pathology in clinical pathology units recommended by the polish society of pathologists. [PDF]

Diagn Pathol
Szylberg Ł, Durślewicz J, Chmura Ł, Rezner W, Bartczak A, Marszałek A.   +5 more
europepmc   +1 more source