Results 121 to 130 of about 36,482,451 (268)

Feature Importance Analysis and Machine Learning for Alzheimer’s Disease Early Detection: Feature Fusion of the Hippocampus, Entorhinal Cortex, and Standardized Uptake Value Ratio

Digital Biomarkers
Introduction: Alzheimer’s disease (AD) is a progressive neurological disorder characterized by mild memory loss and ranks as a leading cause of mortality in the USA, accounting for approximately 120,000 deaths per year.
Aya Hassouneh, Bradley Bazuin, Alessander Danna-dos-Santos, Ilgin Acar, Ikhlas Abdel-Qader   +4 more
doaj   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Toward Personalized Orthopedic Care: Validation of a Smart Knee Brace

Digital Biomarkers
Introduction: Wearable technology offers a promising solution to advance current rehabilitation strategies for post-operative orthopedic care. The aim of this study was to determine the level of agreement and concurrent validity of a smart knee brace ...
Annah McPherson, Andrew J. McDaid, Sarah Ward   +2 more
doaj   +1 more source

Surrogate‐Optimized Flow‐Guided Miniature Condenser for Rapid Exhaled Glucose Detection

Advanced Materials Technologies, EarlyView.
A surrogate‐optimized miniature condenser guides humid exhaled flow toward cold surfaces to accelerate exhaled breath condensate collection. By improving vapor access within a compact footprint, the design increases sample yield. This enables post‐collection enrichment and rapid colorimetric glucose detection from dilute exhaled biomarkers within a 5 ...
Yiming Thomas Lu, Yamin Mansur, Sai Peri, Jiangyuan Wan, Amio Pronoy Das Ritwik, Emily L. Johnson, Jingcheng Ma   +6 more
wiley   +1 more source

eHealth and mHealth in Antimicrobial Stewardship Programs

Digital Biomarkers
Background: The global need for rapid diagnostic methods for pathogen identification and antimicrobial susceptibility testing (AST) is underscored by the increasing bacterial resistance and limited therapeutic options, especially critical in sepsis ...
Felipe Francisco Tuon, Tiago Zequinao, Marcelo Silva da Silva, Kleber Oliveira Silva   +3 more
doaj   +1 more source

Recent Advances in Light‐Addressable Electrochemistry for Spatially Resolved Applications

Advanced Materials Technologies, EarlyView.
This comprehensive review highlights light‐addressable electrochemistry as a powerful tool that uses light to control localized chemical reactions on unstructured semiconductor surfaces. The work evaluates advanced strategies to optimize electrode materials for enhanced spatial resolution and stability. Furthermore, it showcases diverse applications in
Nhi Trang Vo, Sina Jamali, Nam‐Trung Nguyen   +2 more
wiley   +1 more source

Circulating Biomarkers and Targeted Therapy in Pleural Mesothelioma

Pleural mesothelioma (PM) is a rare and aggressive cancer. Standard of care for unresectable disease consists of chemotherapy, vascular endothelial growth factor inhibition, immunotherapy, or combinations thereof.
Bazhenova, Lyudmila, Karen M. Yun, Christopher R. Grant, Lyudmila Bazhenova, Yun, Karen M., Grant, Christopher R.   +5 more
core   +1 more source

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

Advanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen, Dandan Dong, Jinling Liao, Naikai Liao, Mengqi Liu, Qin Zhang, Siting Chen, Qi Liu, Ying Lu, Tianyu Li, Chunlin Zou, Qiong Song, Qiuyan Wang, Jian Liang, Qiji Xie, Chengyang Li, Mengyun Wang, Jiwen Cheng, Zengnan Mo, Gong‐Hong Wei   +19 more
wiley   +1 more source

Plasma Biomarkers and Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer: New Tools for Better Patient Selection?

, 2019
Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for patients with non-small cell lung cancer (NSCLC). Although some patients can experience important response rates and improved survival, many others do not benefit from ICIs ...
Etienne Giroux Leprieur, Adrien Costantini, Jean-François Emile, Thierry Chinet, Coraline Dumenil, Paul Takam Kamga   +5 more
core   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

Advanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas, Ankan Dutta, Shuvendu Das, Abu Musa Abdullah, Wanqing Zhang, Fatema Tuz Zohra, Huanyu Cheng   +6 more
wiley   +1 more source