Results 11 to 20 of about 36,482,451 (268)
Using smartphone sensors for ataxia trials: consensus guidance by the Ataxia Global Initiative Working Group on Digital-Motor Biomarkers [PDF]
, 2023 Smartphone sensors are used increasingly in the assessment of ataxias. To date, there is no specific consensus guidance regarding a priority set of smartphone sensor measurements, or standard assessment criteria that are appropriate for clinical trials ...
Dukart, Juergen +2 more
core +1 more source
Determining cut-points for Alzheimer's disease biomarkers: statistical issues, methods and challenges. [PDF]
, 2012 New proposed criteria for the clinical diagnosis of Alzheimer's disease increasingly incorporate biomarkers, most of which are normally measured on a continuous scale. Operationalizing such criteria thus requires continuous biomarkers to be dichotomized,
Skillbäck, Tobias, +10 more
core +1 more source
Emerging Biomarkers for Immunotherapy in Glioblastoma
, 2022 Immunotherapy has shown clinical benefits in several solid malignancies—in particular, melanoma and non-small cell lung cancer. However, in other solid tumours such as glioblastoma (GBM), the response to immunotherapy has been more variable, and ...
Nadia Mensali, Else Marit Inderberg
core +1 more source
Biomarkers and Lung Cancer Early Detection: State of the Art
, 2021 Lung cancer burden is increasing, with 2 million deaths/year worldwide. Current limitations in early detection impede lung cancer diagnosis when the disease is still localized and thus more curable by surgery or multimodality treatment.
Fabrizio Bianchi +6 more
core +1 more source
The Current Landscape of Glioblastoma Biomarkers in Body Fluids
, 2023 Glioblastoma (GBM) is a highly aggressive and lethal primary brain cancer that necessitates early detection and accurate diagnosis for effective treatment and improved patient outcomes.
Mohammad Doroudian +5 more
core +1 more source
Serum-Exosome-Derived miRNAs Serve as Promising Biomarkers for HCC Diagnosis
, 2022 Background: Serum exosomes are emerging as key liquid biopsy biomarkers for the early diagnosis of cancer. However, the proportion and distribution of small RNA (sRNA) species from serum exosomes of hepatocellular carcinoma (HCC) patients remain unclear.
Ning Tang +6 more
core +1 more source
Digital Biomarkers, 2021 Background: Assuring adequate antibiotic tissue concentrations at the point of infection, especially in skin and soft tissue infections, is pivotal for an effective treatment and cure.
Noé Brasier +10 more
doaj +1 more source
Digital Biomarkers, 2022 Background: While digital phenotyping smartphone apps can collect vast amounts of information on participants, less is known about how these data can be shared back.
Luke Scheuer, John Torous
doaj +1 more source
Proteomic candidate biomarkers of drug-induced nephrotoxicity in the rat [PDF]
, 2012 Improved biomarkers of acute nephrotoxicity are coveted by the drug development industry, regulatory agencies, and clinicians. In an effort to identify such biomarkers, urinary peptide profiles of rats treated with two different nephrotoxins were ...
Hanig, J. +23 more
core +2 more sources
Pathological Digital Biomarkers: Validation and Application
, 2022 Digital pathology offers powerful tools for biomarker discovery, analysis, and translation. Despite its advantages, the clinical adoption of digital pathology has been slow.
Youngjae Song +3 more
core +1 more source