Results 91 to 100 of about 3,004,176 (304)

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Interview with Harold A. Dunkelberger, July 29, 1999

, 1999
The first of two interviews, Harold A. Dunkelberger, a student and professor at Gettysburg College, was interviewed on July 29, 1999 by Michael J. Birkner & David Hedrick.
Birkner, Michael J., Dunkelberger, Harold A., Hedrick, David   +2 more
core  

Language switching in a digital library; does it make a difference if the default language is set to Maori? [PDF]

, 2004
In this paper we investigate the effect of default interface language on usage patterns of the Niupepa digital library (a collection of historic Māori language newspapers), by switching the default interface language between Māori and English in ...
Cunningham, Sally Jo, Don, Katherine J., Keegan, Te Taka Adrian Gregory   +2 more
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Evaluasi Pemanfaatan Koleksi Buku Digital oleh Mahasiswa Pendidikan Dokter di Unit Perpustakaan Fakultas Kedokteran Universitas Gadjah Mada (FK UGM)

Berkala Ilmu Perpustakaan dan Informasi, 2015
Role and function of library unit of medical faculty of Gajah Mada university prepares instrument and support facilities for student of medical education, namely preparing many kinds of information sources in health and medical unit.
Sukirno Sukirno
doaj   +1 more source

Digital Audio Collections

Dalhousie Journal of Interdisciplinary Management, 2010
This paper is about the possibility of libraries creating digital music or audio collections based on the current state of the digital music industry, and in comparison with the difficulties librarians have found in adding e-books to collections. In comparing the e-book and digital music markets, factors such as digital rights management (DRM) and the ...
openaire   +2 more sources

Visualizing Digital Collections [PDF]

Technical Services Quarterly, 2014
Data visualizations can greatly enhance search in digital collections by providing information about the scope and context of a collection and allowing users to more easily browse and explore the contents. This article discusses the benefits of incorporating visualizations into digital collections based on the experiences of the Cold War International ...
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source