Results 41 to 50 of about 1,385,411 (314)

Wasserstein GAN and Waveform Loss-Based Acoustic Model Training for Multi-Speaker Text-to-Speech Synthesis Systems Using a WaveNet Vocoder

open access: yesIEEE Access, 2018
WaveNet, which learns directly from speech waveform samples, has been used as an alternative to vocoders and achieved very high-quality synthetic speech in terms of both naturalness and speaker similarity even in multi-speaker text-to-speech synthesis ...
Yi Zhao   +5 more
doaj   +1 more source

Social Facebook With Big Six Approaches for Improved Students’ Learning Performance and Behavior: A Case Study of a Project Innovation and Implementation Course

open access: yesFrontiers in Psychology, 2020
In Taiwan, classroom lectures are gradually shifting from traditional to diverse digital learning environments through social network websites. Facebook is being used to provide a space for sharing and discussing learning materials and knowledge for ...
Yu-Sheng Su, Hong-Ren Chen
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Why we need to find time for digital humanities: presenting a new partnership model at the University of Sussex

open access: yesInsights: The UKSG Journal, 2017
Recognizing that academic libraries should develop and nurture strong, mutually beneficial relationships with researchers in digital humanities, the authors believe it is strategically important to invest time and resources exploring ideas and partnering
Jane Harvell, Joanna Ball
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Determinants in the online distribution of digital content: An exploratory analysis [PDF]

open access: yes, 2012
Copyright @ 2012 Queen's University of BelfastThis article shows the phases – and discusses the results – of an empirical analysis addressing the legal business models that are adopted online to distribute digital content.
Nuccio, M.   +13 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Digital curation bibliography: preservation and stewardship of scholarly works [PDF]

open access: yes, 2012
In a rapidly changing technological environment, the difficult task of ensuring long-term access to digital information is increasingly important. This publication presents over 650 English-language articles, books, and technical reports that are useful
Bailey, Charles   +3 more
core   +1 more source

How to Successfully Orchestrate Content for Digital Agriecosystems

open access: yes, 2023
Since the 2000s, digital ecosystems have been affecting markets—Facebook and Uber being prominent examples. Looking at the agrisector, however, there is not yet a winner-takes-all solution in place.
Heinz Bernhardt   +4 more
core   +1 more source

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