Results 61 to 70 of about 1,385,411 (314)

Tecnologia Beacon e Storytelling per i Musei. Il Progetto Tap the Artwork

Archeomatica, 2016
In this article we explain TAP THE ARTWORK (ARTAP), a project by Heritage Srl, an innovative startup based in Turin that works in the field of Smart Cultural Heritage.
Elisabetta Bruno, Pietro Tosco
doaj   +2 more sources

Enabling data linkages for rare diseases in a resilient environment with the SERDIF framework

npj Digital Medicine
Environmental factors amplified by climate change contribute significantly to the global burden of disease, disproportionately impacting vulnerable populations, such as individuals with rare diseases.
Albert Navarro-Gallinad, Fabrizio Orlandi, Jennifer Scott, Enock Havyarimana, Neil Basu, Mark A. Little, Declan O’Sullivan   +6 more
doaj   +1 more source

Semantics-Based Content Extraction in Typewritten Historical Documents [PDF]

, 2005
This paper presents a flexible approach to extracting content from scanned historical documents using semantic information. The final electronic document is the result of a "digital historical document lifecycle" process, where the expert knowledge of ...
A. Antonacopoulos, D. Karatzas, Karatzas, Dimosthenis, Antonacopoulos, Apostolos   +3 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Integrating computational thinking, game design, and design thinking: a scoping review on trends, applications, and implications for education

Humanities & Social Sciences Communications
This study integrated the fields of computational thinking (CT), game design, and design thinking through a scoping review, exploring their research development trends, as well as their applications and implications for education.
Chih-Hung Wu, Yu-Cheng Chien, Mei-Tzu Chou, Yueh-Min Huang   +3 more
doaj   +1 more source

The exploration of continuous learning intention in STEAM education through attitude, motivation, and cognitive load

International Journal of STEM Education, 2022
Highlights The STEAM learning cycle was proposed to describe four phases for successful STEAM learning. Affect factors of learning intention in STEAM education were investigated.
Chih-Hung Wu, Chih-Hsing Liu, Yueh-Min Huang   +2 more
doaj   +1 more source

Content-based access to digital video: the Físchlár system and the TREC video track [PDF]

, 2001
This short paper presents an overview of the Físchlár system - an operational digital library of several hundred hours of video content at Dublin City University which is used by over 1,000 users daily, for a variety of applications.
Smeaton, Alan F.
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

That's 'é' not 'þ' '?' or '☐': a user-driven context-aware approach to erroneous metadata in digital libraries

, 2011
In this paper we present a novel system for user-driven integration of name variants when interacting with web-based information systems. The growth and diversity of online information means that many users experience disambiguation and collocation ...
Nichols, David M., Bainbridge, David, David M. Nichols, David Bainbridge, Twidale, Michael B., Michael B. Twidale   +5 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source