Results 81 to 90 of about 692,001 (304)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Computers & Culture, Issue 2

open access: yes, 2023
Computers & Culture is an interdisciplinary digital pamphlet featuring short essays and notes of relevance to the digital and computers in the wider arts, humanities, and social sciences.
Andrews, Jim   +2 more
core  

The mindfulness-based digital wellbeing retreat: An interpretative phenomenological analysis

open access: yesComputers in Human Behavior Reports
Concerns about the health and wellbeing impacts of online activities, such as gaming and social media, have led to the development of psychological interventions targeting problematic technology use.
Justin Thomas   +3 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

2017-18 Institute for Culture and Society Annual Review

open access: yes, 2018
The Institute for Culture and Society researches transformations in culture and society in the context of contemporary global change. It champions collaborative engaged research in the humanities and social sciences for a globalising digital age.
Institute for Culture and Society (R)   +1 more
core   +1 more source

Behavior Intention Derivation of Android Malware Using Ontology Inference

open access: yesJournal of Electrical and Computer Engineering, 2018
Previous researches on Android malware mainly focus on malware detection, and malware’s evolution makes the process face certain hysteresis. The information presented by these detected results (malice judgment, family classification, and behavior ...
Jian Jiao   +3 more
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Comfort measurement of dry and wet touch: an fMRI study

open access: yesAUTEX Research Journal
In order to clarify the brain perception mechanism of tactile discomfort caused by wet fabric on the skin, and compare the changes of brain response to dry and wet tactile stimulation of the skin, five kinds of knitted mid-tube compression socks were ...
Yuan Jie, Lou Lin
doaj   +1 more source

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