Results 61 to 70 of about 5,998,935 (366)

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Narrowing the age‐based digital divide: Developing digital capability through social activities

open access: yesInformation Systems Journal, 2022
Healthcare information technologies (HIT) have shown great potential for improving the effectiveness and quality of healthcare services. However, the inequal ability of older adults to use HIT may limit their exploitation of these benefits. To narrow the
Yang Zhao   +3 more
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Based on capital theory to exploring the digital health divide and determinants among urban and rural older adults in China: Cross-sectional study

open access: yesDigital Health
Background The rapid development of Information and Communications Technology has made eHealth a transformative force in healthcare. However, it has also exacerbated the “digital health divide.” While urban older adults benefit from easier access to ...
Yanbin Yang   +4 more
doaj   +1 more source

Telehealth and the digital divide as a social determinant of health during the COVID-19 pandemic

open access: yesNetwork Modeling Analysis in Health Informatics and Bioinformatics, 2021
Telehealth has been shown to have comparable health outcomes in terms of patient-physician communication, and patient satisfaction and engagement. Nevertheless, the digital divide has exacerbated the social and economic factors that create barriers to ...
C. Clare
semanticscholar   +1 more source

Scaling the Digital Divide: Home Computer Technology and Student Achievement [PDF]

open access: yes, 2010
Assesses the effect of access to home computers and broadband Internet on students' math and reading test scores and its potential to close the achievement gap for the disadvantaged.
Helen F. Ladd, Jacob L. Vigdor
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Economic Inequality, the Digital Divide, and Remote Learning During COVID-19

open access: yesThe Review of Black political economy, 2021
Wealth and education establish a cycle of intergenerational inequality. Wealthier households can provide more educational opportunities for their children, who then will have more chances to build wealth for themselves.
Dania V. Francis, C. Weller
semanticscholar   +1 more source

Teaching with wikis: addressing the digital divide [PDF]

open access: yes, 2008
This paper addresses some aspects of the digital divide affecting teachers and learners in higher education. These relate to divisions arising from variable rates of technology adoption by teachers, which may be especially problematic when students ...
Benson, Robyn   +2 more
core  

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

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