Results 41 to 50 of about 171,523 (302)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Sensors, 2016 Timely and efficient monitoring of crop phenology at a high spatial resolution are crucial for the precise and effective management of agriculture. Recently, satellite-derived vegetation indices (VIs), such as the Normalized Difference Vegetation Index ...
Yang Zheng +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Remote Sensing, 2018 Understanding the progression of host–pathogen interaction through time by hyperspectral features is vital for tracking yellow rust (Puccinia striiformis) development, one of the major diseases of wheat.
Yue Shi +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Satellite detection of increases in global land surface evapotranspiration during 1984-2007
, 2012 As a key component of digital earth, remotely sensed data provides the compelling evidence that the amount of water vapour transferred from the entire global surface to the atmosphere increased from 1984 to 2007.
Yunjun Yao +11 more
core +1 more source
Fusion of Airborne Discrete-Return LiDAR and Hyperspectral Data for Land Cover Classification
Remote Sensing, 2015 Accurate land cover classification information is a critical variable for many applications. This study presents a method to classify land cover using the fusion data of airborne discrete return LiDAR (Light Detection and Ranging) and CASI (Compact ...
Shezhou Luo +6 more
doaj +1 more source
ScienceEarth: A Big Data Platform for Remote Sensing Data Processing
Remote Sensing, 2020 Mass remote sensing data management and processing is currently one of the most important topics. In this study, we introduce ScienceEarth, a cluster-based data processing framework.
Chen Xu +3 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Remote Sensing, 2019 Permafrost is widely distributed in the Tibetan Plateau. Seasonal freeze−thaw cycles of permafrost result in upward and downward surface displacement.
Xuefei Zhang +7 more
doaj +1 more source