Results 51 to 60 of about 171,523 (302)

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

The myth of the Digital Earth between fragmentation and wholeness [PDF]

open access: yes, 2014
Daring predictions of the proximate future can establish shared discursive frameworks, mobilize capital, and steer complex processes. Among the prophetic visions that encouraged and accompanied the development of new communication technologies was the ...
Ballatore, Andrea
core  

Constructing a High-Accuracy Geometric Model for Moon-Based Earth Observation

open access: yesRemote Sensing, 2019
The Moon provides us with a long-term, stable, and unique place for Earth observation. Space agencies of various countries, including the United States, China, and Italy, have made the realization of Moon-based Earth observation an objective of their ...
Yixing Ding   +6 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Declaration of the Earth Observation Summit [PDF]

open access: yes, 2003
This single page document is a declaration of the participants of the Earth Observation Summit held in Washington DC, adopted on July 31, 2003. An affirmation for the need for timely, quality, long-term, global information as a basis for sound decision ...
[Earth Observation Summit]
core  

Remote Estimation of Nitrogen Vertical Distribution by Consideration of Maize Geometry Characteristics

open access: yesRemote Sensing, 2018
The vertical leaf nitrogen (N) distribution in the crop canopy is considered to be an important adaptive response of crop growth and production. Remote sensing has been widely applied for the determination of a crop’s N status.
Huichun Ye   +5 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Application and Validation of a Model for Terrain Slope Estimation Using Space-Borne LiDAR Waveform Data

open access: yesRemote Sensing, 2018
The terrain slope is one of the most important surface characteristics for quantifying the Earth surface processes. Space-borne LiDAR sensors have produced high-accuracy and large-area terrain measurement within the footprint.
Xuebo Yang   +5 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Automatic Detection of Low-Rise Gable-Roof Building from Single Submeter SAR Images Based on Local Multilevel Segmentation

open access: yesRemote Sensing, 2017
Low-rise gable-roof buildings are a typical building type in shantytowns and rural areas of China. They exhibit fractured and complex features in synthetic aperture radar (SAR) images with submeter resolution. To automatically detect these buildings with
Jinxing Chen   +5 more
doaj   +1 more source

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