Results 61 to 70 of about 171,523 (302)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

SAHARA: A Simplified AtmospHeric Correction AlgoRithm for Chinese gAofen Data: 1. Aerosol Algorithm

Remote Sensing, 2017
The recently launched Chinese GaoFen-4 (GF4) satellite provides valuable information to obtain geophysical parameters describing conditions in the atmosphere and at the Earth’s surface. The surface reflectance is an important parameter for the estimation
Lu She, Linlu Mei, Yong Xue, Yahui Che, Jie Guang   +4 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Systematic Comparison of Power Corridor Classification Methods from ALS Point Clouds

Remote Sensing, 2019
Power corridor classification using LiDAR (light detection and ranging) point clouds is an important means for power line inspection. Many supervised classification methods have been used for classifying power corridor scenes, such as using random forest
Shuwen Peng, Xiaohuan Xi, Cheng Wang, Pinliang Dong, Pu Wang, Sheng Nie   +5 more
doaj   +1 more source

Analytical geospatial Digital Earth

International Journal of Digital Earth, 2014
Digital Earth is a virtual representation of the planet, encompassing all its systems and forms, including human societies, manifested as a multidimensional, multiscale, multitemporal, and multilay...
Bert Veenendaal, Songnian Li, Suzana Dragicevic, Maria Antonia Brovelli   +3 more
openaire   +2 more sources

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Modeling the Footprint and Equivalent Radiance Transfer Path Length for Tower-Based Hemispherical Observations of Chlorophyll Fluorescence

Sensors, 2017
The measurement of solar-induced chlorophyll fluorescence (SIF) is a new tool for estimating gross primary production (GPP). Continuous tower-based spectral observations together with flux measurements are an efficient way of linking the SIF to the GPP ...
Xinjie Liu, Liangyun Liu, Jiaochan Hu, Shanshan Du   +3 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Capabilities of Chinese Gaofen-3 Synthetic Aperture Radar in Selected Topics for Coastal and Ocean Observations

Remote Sensing, 2018
Gaofen-3 (GF-3), the first Chinese spaceborne synthetic aperture radar (SAR) in C-band for civil applications, was launched on August 2016. Some studies have examined the use of GF-3 SAR data for ocean and coastal observations, but these studies ...
Xiao-Ming Li, Tianyu Zhang, Bingqing Huang, Tong Jia   +3 more
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source