Results 71 to 80 of about 621,841 (302)

Proto-editions: Historians and the "Something between digital image and digital scholarly edition"

open access: yes, 2023
The paper discusses forms of digital representation of texts that become only available through digital means, in particular the combined publication of digital images and structured data, which I suggest to call "proto-edition".
openaire   +4 more sources

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

"Digital Editing and Curation" (Spring 2016) graduate seminar syllabus

open access: yes, 2016
The attached syllabus was written for my graduate seminar "Digital Editing and Curation," taught to 8 PhD students/candidates at UNC Chapel Hill in Spring 2016.
Whitney Trettien
core   +1 more source

Poaching museum collections using digital 3D technologies

open access: yesJournal of Science and Technology of the Arts, 2015
This paper investigates the creative engagement with digital 3D models of museum artefacts and gives insight into new uses of museum collections enabled by digital scanning, editing and 3D printing technologies.
Sarah Younan
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Mini project : digital video editing : document transcript

open access: yes, 2010
This is Mini Project documentation about digital video editing. It is part of the 2009/10 BSc ( Hons ) in Multimedia Technology (course number 2ELE0075) from the University of Hertfordshire.
University of Hertfordshire, School of Electronic Communications and Electrical Engineering
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Reflections on Textual Editing in the Time of the History of the Book

open access: yes, 2013
This article expresses the need for an approach to scholarly editing that is more historically rooted than has hitherto been the case in Anglo-American textual criticism.
Van Mierlo, Wim
core  

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