Results 51 to 60 of about 2,820,561 (298)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Digital evidences in criminal proceedings: problems of authenticity and admissibility

open access: yesАналітично-порівняльне правознавство
Everyday life is filled with information technology, which is developing very rapidly. In all of this, digital evidence has its place and is becoming increasingly important in crime investigations, helping to establish the truth and ensure justice ...
A. A. Shyshenko
doaj   +1 more source

Digitalization of the criminal process: is simplification always for the better?

open access: yesIDP, 2023
Based on monitoring of current foreign criminal procedural legislation and its application, as well as scientists’ points of view, an analysis of the process of digitalization of criminal justice in some leading countries, in particular Ukraine, was ...
Oleksandr Halagan   +3 more
doaj   +1 more source

How Digital Natives Learn and Thrive in the Digital Age: Evidence from an Emerging Economy [PDF]

open access: yes, 2020
As a generation of ‘digital natives,’ secondary students who were born from 2002 to 2010 have various approaches to acquiring digital knowledge. Digital literacy and resilience are crucial for them to navigate the digital world as much as the real world;
Ho, Manh-Toan   +11 more
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

A Digital Forensic Readiness Architecture for Online Examinations

open access: yesSouth African Computer Journal, 2018
Some institutions provide online courses to students to ease the courses’ workload. Online courses can also be convenient because the online course content management software conducts marking of tests and examinations.
Ivans Kigwana, H. S Venter
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Regulatory Qualification of a Cross-Disease Digital Measure: Benefits and Challenges from the Perspective of IMI Consortium IDEA-FAST

open access: yesDigital Biomarkers, 2023
Background: Innovative Medicines Initiative (IMI) consortium IDEA-FAST is developing novel digital measures of fatigue, sleep quality, and impact of sleep disturbances for neurodegenerative diseases and immune-mediated inflammatory diseases. In 2022, the
David Nobbs   +9 more
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Digital evidence and its use for criminal proceedings

open access: yesАналітично-порівняльне правознавство
This paper examines the role and admissibility of digital evidence, particularly data derived from instant messaging applications like WhatsApp and Telegram, in criminal proceedings within the legal context of the Slovak Republic.
Jakub Matis
doaj   +1 more source

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