Results 51 to 60 of about 976,955 (294)

The analysis of conditions for preservation of gain-frequency and phase-frequency characteristics optimality under analog and digital filters transformation

Российский технологический журнал, 2020
Prototype filters have wide usage for the design of filters with required quality indexes (QI) of gain-frequency response (GFR). The designed filter is obtained from a prototype filter b means of frequency transformation, which preserves these QI.
A. V. Smirnov
doaj   +1 more source

Two techniques for digital filter design [PDF]

, 1970
Digital controllers, one using a special-purpose computer and the other using a combination of digital and analog techniques, are designed around /1/ computers that simulate the transfer function and interface with the system, and /2/ analog and digital ...
Carroll, C. C., Jones, J. W., Jr., Nagle, H. T., Jr.   +2 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Medical image enhancement using threshold decomposition driven adaptive morphological filter [PDF]

, 2008
One of the most common degradations in medical images is their poor contrast quality. This suggests the use of contrast enhancement methods as an attempt to modify the intensity distribution of the image.
Mahmoud, Tarek A., Marshall, Stephen
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Filtering and Overlapping Data for Accuracy Enhancement of Doppler-Based Location Method

Sensors
The localization of radio emitters is a fundamental task in reconnaissance systems, and it has become increasingly important with the evolution of mobile networks.
Rafał Szczepanik, Jan M. Kelner
doaj   +1 more source

Polyphase networks, block digital filtering, LPTV systems, and alias-free QMF banks: a unified approach based on pseudocirculants [PDF]

, 1988
The relationship between block digital filtering and quadrature mirror filter (QMF) banks is explored. Necessary and sufficient conditions for alias cancellation in QMF banks are expressed in terms of an associated matrix, derived from the polyphase ...
Mitra, Sanjit K., Vaidyanathan, P. P.
core   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source