Results 51 to 60 of about 320,258 (311)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A Coarse Alignment Method Based on Digital Filters and Reconstructed Observation Vectors

open access: yesSensors, 2017
In this paper, a coarse alignment method based on apparent gravitational motion is proposed. Due to the interference of the complex situations, the true observation vectors, which are calculated by the apparent gravity, are contaminated.
Xiang Xu   +4 more
doaj   +1 more source

Design of multi-decimation rate digital filter for sigma-delta ADC

open access: yesDianzi Jishu Yingyong, 2022
Based on the standard 0.18 μm process, a digital decimation filter applied to the Sigma-Delta analog-to-digital converter is designed, which can change the decimation rate and adapt to different signal bandwidths. The filter adopts multi-stage decimation
Wang Yao, Bu Gang
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Color-decoupled photo response non-uniformity for digital image forensics [PDF]

open access: yes, 2012
The last few years have seen the use of photo response non-uniformity noise (PRNU), a unique fingerprint of imaging sensors, in various digital forensic applications such as source device identification, content integrity verification and authentication.
Chang-Tsun Li   +3 more
core   +1 more source

The analysis of conditions for preservation of gain-frequency and phase-frequency characteristics optimality under analog and digital filters transformation

open access: yesРоссийский технологический журнал, 2020
Prototype filters have wide usage for the design of filters with required quality indexes (QI) of gain-frequency response (GFR). The designed filter is obtained from a prototype filter b means of frequency transformation, which preserves these QI.
A. V. Smirnov
doaj   +1 more source

Comparing Different Filter-Parameter for Pre-Processing of Brain-Stimulation Evoked Motor Potentials

open access: yesBrain Sciences, 2021
Background: Brain stimulation motor-evoked potentials (MEPs) are transient signals and not periodic signals, and thus, they differ significantly in their properties from classical surface electromyograms.
Volker R. Zschorlich   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy