Results 71 to 80 of about 5,255,523 (302)

Experimental study on the biomechanical loading of a four-dimensional plate for the fixation of femoral shaft fractures

open access: yesBMC Musculoskeletal Disorders
Objective To explore the biomechanical properties of a four-dimensional structure locking osteosynthesis plate that can alter its structure and functionality over time.
Meiling Song   +7 more
doaj   +1 more source

Double-trajectory lumbar screw placement guided by a set of 3D-printed surgical guide templates: a cadaver study

open access: yesBMC Musculoskeletal Disorders, 2021
Background To improve the strength of posterior spine fixation in patients with osteoporosis, some scholars have proposed a method of simultaneously inserting traditional pedicle screws and cortical bone trajectory screws into the pedicle.
Yonghui Zhao   +4 more
doaj   +1 more source

Digital labour shortage: a new divide in library and information studies education? [PDF]

open access: yes, 2011
This paper offers a preliminary reflection on the degree to which the concept of 'digital labour' appears in current library and information studies (LIS) education language, including in course titles, course descriptions, and course content.
Samek, Toni, Worman, Anthony
core  

Digital Ecosystems: Ecosystem-Oriented Architectures

open access: yes, 2011
We view Digital Ecosystems to be the digital counterparts of biological ecosystems. Here, we are concerned with the creation of these Digital Ecosystems, exploiting the self-organising properties of biological ecosystems to evolve high-level software ...
Briscoe, Gerard   +2 more
core   +1 more source

Thermodynamics of Benford's first digit law [PDF]

open access: yesAmerican Journal of Physics, 2019
According to Benford's first digit law, the frequency of appearance of the first digit d taken from various sets of data is log(1+(1/d)) where d = 1, 2,…9. I present a thermodynamic derivation of this law that follows from the unbiased partitioning of a conserved quantity whose pieces may fragment and combine.
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

The First World War Letters of H.J.C. Peirs: A Digital History

open access: yes, 2019
This poster provides a high-level overview of The First World War Letters of H.J.C. Peirs: A Digital History project, giving information on its creation, the collection of letters, how it has used digital mapping, and its use in the ...
Isherwood, Ian A.   +2 more
core  

Computational sense: the role of technology in the education of digital librarians [PDF]

open access: yes, 2006
The rapid progress of digital library technology from research to implementation has created a force for change in the curricula of library schools. The education of future librarians has always had to adapt to new technologies but the pace, complexity ...
Nichols, David M., Twidale, Michael B.
core   +1 more source

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